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This study formulated and characterized a dutasteride-loaded nanocrystalline suspension for long-acting parenteral delivery, finding that it provided sustained drug release in rats with a significant reduction in local inflammation over 28 days following intramuscular injection.

This review discusses new developments in understanding the structure and properties of keratin fiber cell membrane complexes, without reporting new experimental results.

This case study reports a peculiar variant of an epidermal cyst in a patient, featuring unique characteristics like brownish, lumpy contents resembling bone marrow.

This study found that desmosomal cadherin desmoglein 3 loses its rigidity upon Ca2+ removal, regardless of desmosome functional state, suggesting a central role for signaling in hyper-adhesion.

The document concludes that a compound with potential for treating prostate cancer and hair loss was successfully made and its detailed structure was confirmed.

This study found that using a PEG-400/oleic acid mixture as an optical clearing agent enhanced the detection depth of particles in skin without causing dehydration, based on tests in rats and further testing in vivo.

In this study, researchers developed a method using stencils to create controlled stiffness gradients in alginate hydrogels, revealing that stiffer regions within the gels promote deeper invasion by breast cancer cells, facilitating the study of mechanosensitive cellular behaviors.

This study demonstrated that molecular dynamics simulations of keratin could effectively model the mechanical properties of hair, aligning well with experimental data, especially when conducted in vacuum conditions.

This study found that while short-term use of PEG-400 and Thiazone affected rat skin structure, the changes were reversible with no long-term effects observed.

This article describes a method using the CUBIC protocol to clarify and visualize molecular and cellular interactions in mouse skin biopsies at single cell resolution, but does not provide new biological findings.

The study found that a polymer treatment changes the charge on hair surfaces, making bleached hair smoother and less porous.

This study proposed the existence of a membrane-like structure between the cuticle and cortex in human hair, which may provide strong protection against external stimuli.

This study found that keratin fibers like human hair undergo thermal and mechanical transitions that can help assess changes from cosmetic processes such as bleaching and perm-waving.

Hair follicles form hard α-keratin filaments in four steps, showing structural differences.

Cold waving solutions quickly reduce cystine to cysteine in hair.

This study suggests that increased amounts of less stable disulfide conformers in hair shafts may be linked to the brittleness observed in trichothiodystrophy.

This study observed unique ultrastructural changes in a 4-year-old girl with pili trianguli et canaliculi that may affect hair shaft surface characteristics due to inner root sheath alterations.

Different hair types from various ethnic groups affect hair shine due to characteristics like thickness and shape.

This study found that the molecular structures of α-keratin and collagen in a 2,100-year-old female cadaver's hair and tendon were preserved, while fibrous molecule aggregations were altered.

This study found that at pH 9.0, CYS penetrated less and caused less damage to virgin human hair than TG because it barely reached the cortex region.

Oxidized trichocyte keratin has a helical dislocation in its structure.

The researchers reported that components of keratinocytes influence the formation and differentiation of the stratum corneum, the epidermis's most specialized layer.

In this study, certain cysteine residues in Romney sheep wool fibers were labeled more often during stretching tests, particularly under wet conditions, suggesting variability in their disulfide bond contributions to fiber mechanics depending on hydration.

This study found that liquid crystalline nanoparticles formulated with Cremophor surfactants significantly enhanced skin permeation of finasteride compared to lower surfactant concentrations.

Polisorbate 20 is not suitable for curl creams due to instability.

This study examined developing hair cortex with electron microscopy and found that keratin fibrils form between specific regions in hair follicles and aggregate into twisted cables.

This study analyzed the geometric and electronic properties of baicalin conformers, finding that BCLa2TT and BCLa1TT conformers exhibit high stability in aqueous solutions and are favorable for interactions with positively charged species.

This review discusses the structure, types, and distribution of keratins and their role in tissue fragility disorders, particularly within the oral cavity, without presenting new clinical findings.

In this study, researchers developed a new Supported Ionic Liquid Phase palladium catalyst that showed effectiveness in aminocarbonylation reactions for synthesizing pharmaceutical compounds like CX-546 and a precursor of Finasteride, though results were sensitive to substrate variations and prompted palladium leaching concerns.