35 citations
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November 1996 in “Journal of the American Academy of Dermatology” This study reports two HIV-infected men with a rare M. canis infection unresponsive to ketoconazole and terbinafine, where itraconazole was effective but prolonged treatment led to only one cure.
13 citations
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June 2012 in “European journal of medical genetics” In this study, researchers observed monochorionic diamniotic twins with discordant clinical phenotypes, where one had high-grade trisomy 12p mosaicism in certain tissues, while the other showed confined mosaicism likely due to twin-to-twin transfusion.
January 2016 in “ISBN: 978-84-608-9184-0”
November 2023 in “Brain Sciences” This study investigated medications potentially linked to male-factor infertility using the FDA Adverse Event Reporting System and found that finasteride, testosterone, valproate, and other drugs showed significant disproportionate reporting of infertility cases, highlighting a potential under-reporting issue to regulatory bodies.
July 2007 in “Journal of Reproduction & Infertility” This study found that in male rats, finasteride significantly decreased spermatogonia and primary spermatocytes numbers and increased Leydig cells, but did not affect overall testis histology or spermatogenesis.
February 2024 in “Animals” This study found that supplementing pregnant Hanshan white cashmere goats' diets with selenium yeast led to higher birth weights, improved cashmere quality and yield, and enhanced hair follicle development in their offspring, possibly through increased antioxidant capacity.
5 citations
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December 2015 in “Asian pacific Journal of Tropical Biomedicine” In this study, the aqueous extract from Phthirusa pyrifolia leaves significantly decreased testosterone levels in male Wistar rats without causing liver or kidney damage, suggesting potential effects on libido and reproduction.
This study is the first to document significant age-related pathologies in endangered captive Julia Creek dunnarts, highlighting hormonal dysregulation and reproductive issues in females, while males exhibited higher occurrences of cutaneous diseases and testicular degeneration, providing valuable insight for conservation efforts.
April 2017 in “Reactions Weekly” Finasteride may cause weak ejaculation and reduced semen volume.
7 citations
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January 2015 in “Case reports in genetics” This case report illustrates how SNP array testing helped identify a DCAF17 mutation linked to Woodhouse-Sakati syndrome in consanguineous Qatari siblings with shared features including alopecia and hypogonadotropic hypogonadism.
53 citations
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October 1978 in “Archives of dermatology” This study reports two cases of acquired zinc deficiency presenting with skin symptoms such as hair loss and acrodermatitis, suggesting these manifestations may help in diagnosing zinc deficiency in humans.
2 citations
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October 2000 in “The Journal of Urology” Finasteride daily doesn't affect sperm production or semen in young men.
October 2023 in “Bangladesh journal of urology” This study in Bangladesh reports that 81% of patients with refractory idiopathic hematospermia showed remission after three months of finasteride treatment, significantly higher than the 27% remission rate in the placebo group, with results sustained for some time after stopping the medication.
January 2011 in “Yearbook of Endocrinology” 16 citations
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March 1986 in “Biochemical Pharmacology”
55 citations
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July 2013 in “Dermatologic therapy” This review explores the impact of various medications on male fertility, highlighting reversible negative effects from methotrexate, finasteride, and ketoconazole, while reporting no adverse fertility effects for oral retinoids and certain immunosuppressants.
1 citations
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August 2012 in “Archives of Gynecology and Obstetrics” Finasteride can help induce ovulation and lead to a healthy birth in some women.
January 2013 in “International Journal of Biological Sciences” This study demonstrates that the CRISPR-Cas9 system can be used to successfully edit genes in large mammals, such as Cashmere goats, creating a valuable model for research on EDAR gene-related phenotypes.
October 2024 in “Skin Research and Technology” This report describes several cases of pili annulati in children, highlighting its genetic predisposition and distinctive "zebra stripe" hair pattern, but notes no effective treatment is available.
11 citations
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November 2021 in “The Journal of Clinical Endocrinology and Metabolism” This study found that genetic risk factors for PCOS can lead to nonreproductive phenotypes in men, suggesting these effects are independent of ovarian function.
December 2025 in “Microscopy and Microanalysis” This study found that administering lycopene to rats provided significant protection against the testicular damage caused by finasteride, as indicated by improved sperm parameters, and reduced oxidative stress and apoptosis markers.
This research suggests that the digit ratio, 2D:4D, is unlikely to be a significant indicator of male androgenetic alopecia, contradicting a prominent isolated finding from a previous study.
1 citations
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September 2015 in “Human Andrology” Married Egyptian women with PCOS have lower sexual desire compared to those without PCOS.
47 citations
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August 2014 in “The Journal of Clinical Endocrinology and Metabolism” This study suggests that variations in PCOS phenotypes observed across different ethnic groups may be due to a genetic gradient resulting from historical human migrations and genetic drift.
45 citations
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August 1994 in “Journal of Chromatography B: Biomedical Sciences and Applications” Method detects finasteride in plasma and semen with high sensitivity and accuracy.
37 citations
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January 2009 in “Sexual Development” This study found that chronic exposure to fadrozole or finasteride during frog development induced intersex individuals, which displayed different gene expression profiles depending on the chemical used.
April 2021 in “Animal Bioscience” This study found that 5-aminolevulinic acid significantly improved chicken sperm motility and increased mitochondrial membrane depolarization, while decreasing ATP levels.
18 citations
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July 2020 in “Basic and Clinical Andrology” This article discusses concerns and recommendations from a French-speaking andrology society regarding COVID-19's potential impact on men's reproductive health and calls for further research in this area.
August 2013 in “Fertility and Sterility” This study found that women with PCOS have higher follicular fluid levels of testosterone and IL-6, despite similar NEFA levels to non-PCOS women, suggesting increased lipotoxicity impact on androgenesis in PCOS.
March 2025 in “Journal of Bio Innovation” This review examines the causes, symptoms, diagnosis, and treatment of dermatophytosis (ringworm) in dogs and cats, highlighting the role of Microsporum canis and the public health implications of zoophilic dermatophytes, affecting roughly 20-25% of the global population.