Dermoscopic Features of Pili Annulati: Characteristics of PA

    October 2024 in “ Skin Research and Technology
    Yuantao Song, Meixiang Rong, Xibo Gao, Tiantian Bi, Yangyang Lin, Qinfeng Li
    TLDR Pili annulati causes zebra-striped hair but doesn't affect hair strength or quality of life.
    The study focuses on pili annulati, a rare genetic condition characterized by alternating black and white hair, resembling "zebra stripes." This condition is believed to be autosomal dominant and is caused by the accumulation of bubbles in the hair cortex and medulla. The study involved several children with pale yellow hair at birth, with no history of hair dyeing, but with a family history of the condition. Dermoscopy revealed the characteristic striped pattern, aiding in diagnosis. Pili annulati does not typically lead to hair loss, and there is no effective treatment, though minoxidil has been suggested. The study emphasizes the importance of dermoscopy in diagnosing this condition in pediatric patients and calls for further research due to the small sample size.
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