Ameliorative Potential of Lycopene Against Finasteride-Induced Seminiferous Tubules Damage in Adult Rats: A Histological, Immunohistochemical, and Biochemical Study

    December 2025 in “ Microscopy and Microanalysis ”
    Amany Mohamed Shalaby, Hamad Alsaykhan, Sulaiman Mohammed Alnasser … M. Shehab
    Studysummary This study found that administering lycopene to rats provided significant protection against the testicular damage caused by finasteride, as indicated by improved sperm parameters, and reduced oxidative stress and apoptosis markers.
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    Research cited in this study 17

    1. Protective Role of Hesperidin in Finasteride-Induced Testicular Toxicity in Adult Male Wistar Rats: Insights Into Oxidative Stress, Apoptosis, and Ultrastructure of Seminiferous Tubules Reproductive toxicology · 2024
    2. Resveratrol Ameliorates the Seminiferous Tubules Damages Induced by Finasteride in Adult Male Rats Microscopy and Microanalysis · 2020
    3. In Vivo and In Silico Evaluation of the Ameliorative Effect of Hesperidin on Finasteride-Induced Testicular Oxidative Stress in Wistar Rats Toxicology Mechanisms and Methods · 2020
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