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DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

Heavily hunted wolves have higher stress and reproductive hormone levels.

18β-glycyrrhetinic acid from licorice root is good for skin and hair treatments but has absorption challenges.

PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

The review suggests that a special cell-derived treatment shows promise for various skin conditions and hair growth but needs more research for confirmation.

Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.

Polycystic ovary syndrome (PCOS) was first described in 1721, officially diagnosed in the 1990s, and is now known to be partly genetic and linked to insulin resistance, with increased risk of cardiovascular disease and carbohydrate metabolism issues.

Thiazole, a sulfur and nitrogen chemical, is useful in creating potential drugs for conditions like seizures, cancer, bacterial infections, tuberculosis, inflammation, malaria, viruses, Alzheimer's, diabetes, and A1-receptor issues.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

Medium-dose prednisolone pulse therapy is effective and safe for multifocal alopecia areata but not for more severe forms.

The document concludes that understanding and treatments for alopecia areata have significantly advanced, now recognizing it as an autoimmune disorder.

Type 1 diabetes often occurs with other autoimmune diseases, and personalized treatment based on genetics can improve outcomes.

Moving horses to new places can increase their stress levels, as shown by higher stress hormone in their hair.

Some patients developed hair loss after islet cell transplant possibly due to their immune-suppressing medications.

MR antagonists may improve skin health and wound healing, especially in aging.

Androgen use may increase the risk of stroke, but more research is needed.

Eyelid cells share signaling components but differ in pathway activity.

The glucocorticoid receptor helps protect skin from tumors and other issues.

Platelet-Rich Plasma (PRP) has potential benefits in plastic surgery, especially for skin grafts, wound healing, hair loss, mild Carpal Tunnel Syndrome, and TMJ disorders, but more research is needed to confirm its effectiveness.

Current alopecia treatments manage symptoms but don't cure, and better treatments are needed.

A man got a scalp infection from synthetic hair implants because the procedure wasn't done by a doctor and was poorly managed.

High levels of cortisol in hair are linked to a greater risk of brain aneurysm rupture.

Low-dose chemotherapy is safer, more effective, and cost-effective than surgery for treating bone lesions in children.

Keeping the head elevated for 1.5 days after hair transplant surgery helps prevent facial swelling.

Goat hair shows changes in metal levels and stress when goats move from indoors to mountain pastures.

Mesotherapy might be a useful addition to dental surgery to reduce drug use and side effects, but more research is needed.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

Alopecia areata is an autoimmune disease with genetic links, treatable with certain medications, and can affect mental health.