January 2026 in “Western Journal of Nursing Research” This study found that collecting hair samples for cortisol analysis is feasible in community-dwelling individuals with longstanding multiple sclerosis, although no significant correlation between hair cortisol levels and perceived chronic stress was observed, highlighting the complexity of stress measurement in this population.
489 citations
,
November 2021 in “Signal Transduction and Targeted Therapy” This review discusses the composition, activation, and regulation of the JAK/STAT pathway and highlights its role and inhibitors in various diseases, but reports no new experimental results.
201 citations
,
November 2002 in “Annals of internal medicine” This guideline discusses evidence-based recommendations for managing acute migraine attacks and preventing migraines, highlighting effective treatments such as NSAIDs and triptans but reports no new clinical findings.
91 citations
,
August 2024 in “Acta Pharmaceutica Sinica B” This review explores how microneedles can improve the delivery of dermatological treatments by bypassing the skin's outer barrier, discussing their potential use in managing skin diseases, cosmetic applications, and challenges related to clinical adoption.
68 citations
,
May 2024 in “International Journal of Molecular Sciences” This review of acne management strategies highlights current treatments, such as topical and systemic therapies, procedural methods, and dietary changes, while also discussing emerging options like biologics and probiotics as potential future treatments, emphasizing personalized care due to acne's complex nature.
57 citations
,
October 2021 in “Journal of ethnopharmacology” This review compiled by the authors emphasizes the traditional use of medicinal plants for dermatological disorders in India, highlighting the need for further scientific studies to validate their effectiveness and suggesting potential for drug development based on ethnodermatological practices.
54 citations
,
June 2023 in “International Journal of Molecular Sciences” This review reports that myricetin, a naturally occurring antioxidant in plants, may assist in cancer management by enhancing the effects of existing drugs and inhibiting inflammatory markers, based on in vivo and in vitro studies.
53 citations
,
July 2021 in “International Journal of Molecular Sciences” This study found that extracts from Geranium pyrenaicum show promising antioxidant, enzyme inhibitory, and antiviral activities, particularly the methanolic extract's antiviral activity against HSV-1.
52 citations
,
January 2022 in “Current Research in Pharmacology and Drug Discovery” This review highlights ongoing efforts in drug repurposing and development of new therapeutics against COVID-19, emphasizing the promise of these strategies in addressing the challenges posed by SARS-CoV-2 mutations and post-infection complications.
49 citations
,
May 2020 in “The Scientific World JOURNAL” This position paper from the Italian Mesotherapy Society discusses the application of intradermal therapy based on scientific evidence, highlighting its potential benefits for certain localized conditions, although it acknowledges the lack of randomized clinical trials for some uses.
48 citations
,
January 2024 in “Frontiers in Pharmacology” This paper reviews strategies to enhance the effectiveness of topical drug delivery by addressing skin barrier challenges, optimizing drug delivery systems, and personalizing treatment approaches, highlighting both current advancements and limitations in the field.
41 citations
,
June 2024 in “Journal of Cellular and Molecular Medicine” This study reviews how oxidative stress affects hair follicle development and hair growth, discusses antioxidant-based treatments for hair loss, and evaluates natural antioxidant products that promote hair growth, emphasizing the need for further research due to existing limitations.
24 citations
,
March 2024 in “Antioxidants” In this review, researchers reported that cinnamon and ginger supplementation may benefit PCOS patients by improving hormonal status, lipid profiles, obesity, and insulin resistance through oxidative stress and inflammation reduction.
19 citations
,
October 2024 in “Molecular Pharmaceutics” This review discusses the challenges of traditional phytochemical delivery methods and highlights the potential of microneedles to improve intra/transdermal delivery, reporting no new clinical results.
15 citations
,
March 2023 in “Heliyon” This study found that water-soluble beehive extract exhibited anxiolytic, antidepressant, and anti-inflammatory effects in animal models.
14 citations
,
February 2023 in “Frontiers in Bioengineering and Biotechnology” This review details various components used in hydrogel composites for treating chronic diabetic ulcers and highlights potential future materials but reports no new empirical findings.
14 citations
,
March 2022 in “Journal of Biomedical Science” In this study, Cyanidin 3-O-arabinoside was found to protect against DHT-induced dermal papilla cell senescence and mitochondrial dysfunction in androgenetic alopecia, restoring hair growth in mouse models.
13 citations
,
November 2022 in “Future Journal of Pharmaceutical Sciences” This review examines liposome-based cosmeceuticals for various skin conditions and reports no new clinical results, highlighting the potential promise these formulations offer for future applications.
12 citations
,
October 2021 in “Cells” This review discusses the potential of miRNA-mediated hair growth treatments for androgenetic alopecia by targeting DKK1 to modulate the Wnt/β-catenin signaling pathway and reports no new clinical findings.
12 citations
,
December 2023 in “Antioxidants” In this study, researchers found that blackberry leaves exhibited higher liposoluble antioxidant levels and inhibited lipid peroxidation more effectively than raspberry leaves, while raspberry leaves showed greater water-soluble antioxidant content and hydroxyl radical inhibition in vitro.
11 citations
,
August 2022 in “Evidence-based Complementary and Alternative Medicine” This study found that methanolic extract of Eclipta alba leaves exhibited strong antibacterial effects against certain pathogens including methicillin-resistant Staphylococcus aureus, but it showed no activity against Mycobacterium tuberculosis, including drug-resistant strains.
10 citations
,
December 2020 in “Frontiers in Medicine” This review discusses the molecular differences between male and female responses to SARS-CoV-2 infection and highlights the lack of specific guidelines for altering sex-specific COVID-19 prognoses.
9 citations
,
January 2018 in “International Journal of Trichology” This case report discusses cutaneous graft versus host disease presenting as fibrosing alopecia, suggesting a mechanistic model for understanding cicatricial pattern hair loss.
9 citations
,
August 2024 in “Frontiers in Pharmacology” This review evaluates the potential of natural products and medicinal plants for myocardial infarction treatment, highlighting their therapeutic promise and mechanisms such as reducing oxidative stress and inflammation, but reports no new clinical results.
8 citations
,
February 2025 in “Pharmaceuticals” This source reviews the potential of polyphenols as therapeutic and preventive treatments for common skin disorders such as acne, fungal infections, dermatitis, alopecia, and skin cancer, emphasizing their anti-inflammatory and antimicrobial effects and ability to penetrate the skin barrier.
6 citations
,
March 2022 in “Frontiers in drug discovery” This review summarizes 25 small molecule drugs with in vitro and in vivo data for COVID-19 treatment, highlighting their structural diversity and potential to guide future antiviral discovery.
6 citations
,
November 2021 in “Journal of Ethnopharmacology” This review discusses the traditional uses, chemical components, and biological activities of Calanthe species, reporting no new findings; it underscores the need for conservation and further pharmacological research.
5 citations
,
October 2024 in “International Journal of Molecular Sciences” This study observed that piperonylic acid activated key signaling pathways in dermal papilla cells and increased hair growth markers, and a clinical trial showed users of a piperonylic acid formulation had more hair than those using a placebo, suggesting its potential for treating hair loss.
4 citations
,
September 2025 in “International Journal of Molecular Sciences” This review discusses the dermatological applications and potential health benefits of Epigallocatechin-gallate (EGCG) from green tea, but provides no new clinical findings.
3 citations
,
February 2024 in “Patient Preference and Adherence” In this study, the authors suggest that patient safety with isotretinoin in Palestine can be improved by adapting pharmacy and medical practice protocols to better educate patients and ensure adherence to safety monitoring and laboratory ordering.