Molecular Mechanisms Leading to Sex-Specific COVID-19 Prognosis and Targeted Therapies

    December 2020 in “ Frontiers in Medicine ”
    Thushara Galbadage, Brent M. Peterson, Jeffrey S. Wang … Richard S. Gunasekera
    Studysummary This review discusses the molecular differences between male and female responses to SARS-CoV-2 infection and highlights the lack of specific guidelines for altering sex-specific COVID-19 prognoses.
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    Research cited in this study 4

    1. Impact of Anti-Androgen Therapies on COVID-19 Susceptibility: A Case-Control Study in Male Population from Two COVID-19 Regional Centers of Lombardy, Italy medRxiv (Cold Spring Harbor Laboratory) · 2020
    2. A Preliminary Observation: Male Pattern Hair Loss Among Hospitalized COVID-19 Patients in Spain – A Potential Clue to the Role of Androgens in COVID-19 Severity Journal of Cosmetic Dermatology · 2020
    3. Anti-Androgenic Curcumin Analogues as Steroid 5-Alpha Reductase Inhibitors Medicinal Chemistry Research · 2017
    4. Gender Differences in the Regulation of Blood Pressure Hypertension · 2001