11 citations
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April 2025 in “Pharmaceutics” In this review, researchers explore various treatment options for alopecia, focusing on nano-drug delivery systems using plant-based substances, which are potentially effective and less harmful than current treatments, while also highlighting emerging trends such as 3D bioprinting and plant extracts for future therapies.
8 citations
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February 2022 in “Scientific Reports” This study suggests that 20 vital medicinal herbs may exert therapeutic effects on alopecia by regulating specific target genes and proteins, offering insights into their novel mechanisms distinct from conventional drugs.
7 citations
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December 2019 in “Pharmaceutics” This study found that co-administration of ketoconazole significantly altered the pharmacokinetics of dutasteride in rats, suggesting an interaction potential between dutasteride and azole antifungal drugs.
7 citations
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March 2023 in “Antioxidants” This study confirmed the antioxidant role of rosemary, suggesting its potential use in treating inflammatory and infectious skin conditions, but emphasizes that more large-scale controlled trials are necessary to fully understand its clinical impact.
6 citations
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October 2023 in “Pharmaceuticals” This study found that the extract of Eclipta prostrata L. demonstrated high antioxidant and anti-acetylcholinesterase activities, moderate inhibition of enzymes linked to diabetes, and favorable ADMET properties, suggesting potential cognitive and diabetes management benefits.
3 citations
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January 2022 in “Precision medicine and clinical omics” This study reports that using molecular docking methods, beta-sitosterol and stigmasterol from Serenoa repens were identified as potential natural inhibitors of the 5AR1 enzyme, which could serve as novel treatments for androgenetic alopecia based on their inhibitory action observed in a laboratory setting.
2 citations
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July 2025 in “Journal of Health Population and Nutrition” This study suggests that managing sleep disorders, particularly those involving difficulty initiating sleep, may benefit from dietary interventions that reduce proinflammatory nutrients and increase anti-inflammatory nutrients.
2 citations
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January 2022 in “International Journal of Medical Sciences” In this study, kartogenin promoted hair growth by enhancing cell proliferation and migration in vitro and extended hair length in mice, suggesting its potential as a treatment for hair loss.
2 citations
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October 2022 in “Electrochem” This review explores the applications of phytonutrient-based biosensors in micro-electrochemical systems and reports no new experimental findings, emphasizing the potential and challenges of this innovative approach.
2 citations
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January 2014 in “Journal of clinical and diagnostic research” This review discusses various hair loss treatments, such as stem cell therapy, laser therapies, and mesotherapy, emphasizing their potential and limitations while highlighting the need for further research to address genetic factors in hair loss.
1 citations
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June 2022 in “JAAD case reports” This case report describes a woman who developed toxic epidermal necrolysis, potentially linked to an etonogestrel contraceptive implant, suggesting the need for further research into such adverse reactions.
1 citations
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April 2022 in “Clinical Cosmetic and Investigational Dermatology” In this study, a case of lichen amyloidosis on the scalp significantly improved with a 2-month topical treatment using clobetasol propionate/all-trans retinoic acid ointment.
1 citations
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October 2016 in “Iranian journal of psychiatry and behavioral sciences” This study presents two case reports where patients experienced hair loss during treatment with the SSRI sertraline, highlighting this rare but potential side effect.
November 2025 in “Natural Product Communications” This review compiles evidence indicating that rosemary essential oil may enhance cognitive function, sleep quality, mood, and pain management in aromatherapy; however, it also notes potential allergic reactions, emphasizing caution in its use.
December 2023 in “European Journal of Medicinal Chemistry” This review highlights potential therapeutic mechanisms of natural products for androgenetic alopecia, suggesting they may modulate signaling pathways and have anti-inflammatory and antioxidant effects.
July 2021 in “IntechOpen eBooks” This review discusses the potential of ginseng and its metabolites for treating hair loss and reports no new clinical findings.
October 2017 in “The American journal of gastroenterology” This study reports a case linking the use of the herbal supplement He Shou Wu (Polygonum multiflorum) to acute hepatocellular hepatitis, highlighting potential herb-induced liver injury.
October 2016 in “Iranian journal of psychiatry and behavioral sciences” This case study reports instances of hair loss in two patients taking sertraline, suggesting that even low doses of SSRIs might cause this rare side effect, which could impact treatment adherence.
December 2025 in “Current Issues in Molecular Biology” This study evaluated novel steroids' potential as future hormonal therapies for neuroprotection in glucose disorders, but emphasized that further research is needed to optimize androgen antagonist use in the context of COVID-19 progression.
January 2022 in “International Journal of Nutrology” This review discusses the potential role of nutritional supplements, like lycopene and tranexamic acid, in managing melasma during the COVID-19 pandemic but reports no new clinical outcomes.
November 2022 in “Clinical, Cosmetic and Investigational Dermatology” In this study, a combined treatment for moderate to severe androgenetic alopecia using electric microneedles showed a 100% response rate after 12 weeks, with improvements in hair density and mild side effects, offering promising application prospects.
January 2022 in “International review of movement disorders” In this review, the authors found that cannabinoids and steroid-related drugs show potential for treating Tourette syndrome, but existing evidence is limited and further research is needed to confirm their efficacy and safety.
70 citations
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February 2016 in “EMBO reports” This study identified a subtype of itch-sensing neurons in mice, which express Ret and somatostatin, and found that their ablation reduces scratching induced by certain pruritogens.
35 citations
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November 2021 in “Journal of nanobiotechnology” This study reported that thymol-loaded nanoparticles showed promise as an antibiotic-free treatment for acne by effectively targeting the infection without disrupting healthy skin microbiota.
16 citations
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November 2011 in “Neuroscience Letters” This study reported that progesterone reduces cell death in hippocampal cultures following oxygen–glucose deprivation mainly through its conversion to allopregnanolone and the involvement of GABAA receptors.
12 citations
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June 2024 in “Nutrients” In this review, researchers highlighted that natural polyphenolics like flavonoids and resveratrol may help enhance testosterone production in aging males by boosting the expression of the Star gene in Leydig cells, potentially preventing age-related degenerative conditions linked to testosterone insufficiency.
3 citations
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January 2023 in “Agronomy” This research reported that KDML105 bran extract demonstrated antioxidant activities, reduced nitric oxide production, and influenced gene expression related to the hair cycle in cultured dermal papilla cells, suggesting potential as an anti-hair loss agent by supporting the anagen phase and angiogenesis.
January 2017 in “Journal of Dermatology and Venereology” This study found that Naringenin and Hesperetin significantly increased the proliferation of hair-related cells and suggested potential as natural hair growth-promoting agents.
7 citations
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March 2023 in “Pharmacy” In this study, a community pharmacy-based intervention in Serbia was associated with significant improvements in clinical symptoms for patients with post-COVID syndrome.
9 citations
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April 2021 in “Climacteric” This study provides a guideline for the safe and effective use of testosterone in women with hypoactive sexual desire disorder, recommending systemic transdermal testosterone for appropriate candidates while highlighting the importance of informed consent and monitoring due to unestablished long-term safety.