February 2026 in “International Journal of Molecular Sciences” This review discusses the potential benefits of hyperthermia in cancer therapy, combined with natural compounds, to enhance treatment efficacy and reports no new clinical results.
December 2025 in “Journal of Drug Delivery Science and Technology” In mouse studies, this research found that combining ginsenoside Rg3 and glycyrrhizic acid with minoxidil improved treatment outcomes for androgen alopecia by addressing both symptoms and root causes, notably activating the Wnt/β-catenin pathway and promoting hair follicle cell proliferation.
This study reports that Hair RiseTM microemulsion, made from plant extracts, significantly enhanced hair follicle cell growth and improved hair growth signaling pathways, suggesting it as a plant-based alternative for androgenetic alopecia treatment.
32 citations
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September 2018 in “Journal of pharmaceutical sciences” This study extended a skin diffusion model to include a porous pathway, effectively explaining the permeability of both polar and lipophilic solutes through the stratum corneum.
November 2025 in “Journal of Clinical Medicine” This study found that a novel drinkable supplement significantly increased hair density and reduced hair shedding over six months in women with telogen effluvium, although the authors emphasize the need for larger, placebo-controlled trials to confirm these promising results.
3 citations
,
August 2021 in “Clinics in Dermatology” This review discusses various treatments for hair loss, such as topical agents, oral minoxidil, and laser therapies, but reports no new clinical results; debates on issues like post-finasteride syndrome are also covered.
2 citations
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January 2024 in “Pharmaceuticals” This paper reviews the properties, characteristics, and applications of deep eutectic solvents as environmentally friendly alternatives for extracting bioactive compounds from natural sources in the pharmaceutical industry.
June 2023 in “Journal of Cosmetic Dermatology” This study found that a combination therapy of autologous platelet-rich plasma and non-cross-linked hyaluronic acid increased hair density significantly in women with female androgenetic alopecia, without serious adverse effects.
21 citations
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March 2021 in “Molecules” This study found that a new quercetin-loaded self-nanoemulsifying drug delivery system improved quercetin bioavailability by 149.8% compared to its suspension in rats.
14 citations
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September 2023 in “Foods” This review outlines recent advancements in droplet-based microfluidic technology using food-grade emulsions to create diverse delivery systems by controlling droplet size, shape, and dispersity, while also discussing challenges in scaling these processes from laboratory to industrial applications.
3 citations
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April 2023 in “Quality Assurance and Safety of Crops & Foods” This study found that oil extracted from Prinsepia utilis seeds is physicochemically stable and suitable for use in manufacturing ketoconazole soap, which met quality control standards and may provide a cost-effective alternative to expensive additives in cosmetic and pharmaceutical applications.
February 2026 in “Cosmetics” This review highlights that Trigonella foenum-graecum L. (fenugreek) shows promise as a versatile plant-based ingredient in cosmetics due to its phytochemicals, which offer benefits for skin and hair care, although further research is necessary for robust validation.
April 2025 in “BMC Chemistry” This study developed an organic hair conditioner using chitosan-thiadiazole conjugates that showed improved hair detangling, moisture retention, and protection without causing irritation, promising an environmentally sustainable approach to hair care.
9 citations
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June 2023 in “Cells” This review summarizes recent findings on how the dysregulated PI3K/Akt/mTOR pathway contributes to immune-mediated inflammatory skin disorders and discusses the potential of natural products, synthetic compounds, and biologic agents in their treatment. However, it emphasizes the need for further research to develop effective therapies.
40 citations
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March 2022 in “Small” In an animal model, this study found that PEG hydrogels delivering M2 macrophage-derived exosomes effectively promoted M1 to M2 macrophage transition and enhanced wound healing.
1 citations
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January 2021 in “SSRN Electronic Journal” This review discusses the use of nanomaterials in hair cosmetics and treatments and reports no clinical results, highlighting their potential to improve the efficacy and safety of active compounds.
November 2005 in “CRC Press eBooks” This article reviews the development and challenges of skin penetration enhancers, highlighting their limitations in compatibility and safety, and reports no new clinical findings.
September 2023 in “Apple Academic Press eBooks” This review highlights that Salvia rosmarinus, commonly known as rosemary, possesses multiple pharmacological activities, such as antioxidant, anti-inflammatory, and anticancer effects, and is used in medicinal, cosmetic, and food products due to its rich bioactive components.
March 2016 in “RepositóriUM (Universidade do Minho)” Molecular dynamics simulations help understand keratin's properties and predict hair's response to treatments.
1 citations
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January 2023 in “Journal of Clinical Medicine” This paper presents the first reported case of Acute Localized Exanthematous Pustulosis linked to topical minoxidil use, suggesting a contact-induced hypersensitivity reaction as a potential mechanism.
16 citations
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March 2023 in “Clinical Cosmetic and Investigational Dermatology” This study demonstrated that regular use of LactoSporin cream for 10 weeks significantly reduced wrinkles and fine lines in healthy female participants, although improvements in skin elasticity and hydration were not significantly better than placebo when measured by certain instruments.
14 citations
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February 2025 in “Pharmaceutics” This review highlights recent advancements in using niosomes as nanocarriers for improved delivery and sustained release of active cosmetic compounds, discussing their properties, applications, and future potential in cosmetic chemistry.
4 citations
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October 2007 in “PubMed” This study found that the PQ-70 shampoo formulation demonstrated the highest Hair Humidity Resistance Factor, indicating superior anti-frizz performance compared to other tested shampoos.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review reports that herbal cosmetics offer diverse biological benefits, including antioxidant, antibacterial, and moisturizing effects, enhanced by advanced formulation methods, while emphasizing the need for more clinical validation and standardized practices to ensure long-term safety and efficacy.
January 2026 in “International Journal of Cosmetic Science” This study observed that eco-friendly PALF forms a protective physical barrier on the skin, helping limit the impact of environmental pollutants and offering additional benefits for skin and hair in various cosmetic formulations.
June 2025 in “Unram Medical Journal” This review found that linoleic acid, when used in various skincare product formulations such as creams and serums, offers potential benefits for skin regeneration and hair growth, highlighting its promise as a natural, sustainable ingredient in cosmetics.
May 2024 in “Journal of medicinal food” This review highlights jojoba oil's unique composition and its growing therapeutic applications, noting its antioxidant, anti-acne, antidiabetic, and antibacterial properties, as well as its use in various pharmaceutical formulations.
61 citations
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June 2022 in “Journal of Controlled Release” This review discusses the advantages, applications, and current trends of dissolving microneedles for drug delivery across various therapeutic areas and reports no new clinical results.
3 citations
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October 2022 in “International Journal of Impotence Research” This article reviews the role of testosterone in sexual health, supporting Testosterone Replacement Therapy as an effective treatment for Hypoactive Sexual Desire Disorder in postmenopausal women, though more research is needed on its long-term effects and applicability to premenopausal women.
5 citations
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November 2025 in “Biomolecules” This review examines the benefits of topical hyaluronic acid in cosmetic applications, noting its ability to penetrate the skin in low-molecular-weight forms and highlighting safety supported by clinical trials.