January 2024 in “Collagen and leather” This study observed that using an environmentally friendly bovine milk permeate effectively and cleanly removes wool from sheepskins without harming the skin, and results in smoother leather compared to traditional chemical methods.
1 citations
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January 2020 in “VTechWorks (Virginia Tech)” This study found that early treatment with αCT1 in wound healing increased collagen synthesis and disorganization, potentially improving long-term scar appearance by altering early collagen matrix formation.
April 2024 in “UNESP Institutional Repository (São Paulo State University)” In this study, researchers analyzed alpaca skin morphology and found that type I and IV collagen are present in both the epidermis and dermis, while type III collagen is found only in the dermis.
April 2021 in “Journal of Investigative Dermatology” Early-stage skin substitutes improve wound healing and skin structure.
12 citations
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September 2020 in “Stem cell research & therapy” This study concluded that early-stage tissue-engineered skin substitutes, developed using skin progenitor cells, had a better graft efficiency and supported hair follicle formation, which may improve wound healing outcomes.
58 citations
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November 2013 in “Journal of Innovative Optical Health Sciences” This review discusses the development and application of multiphoton microscopy in dermatology, highlighting its advantages and potential future research directions without reporting new clinical results.
29 citations
,
November 2014 in “Experimental Dermatology” This study found that α-MSH administration before skin wounding in adult mice reduced inflammation and scar area, suggesting a potential pathway to more regenerative healing.
7 citations
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January 2016 in “Methods in molecular biology” This report introduces a tissue-engineered nerve conduit combining hfNCSCs-derived neurons and acellular nerve grafts to potentially repair long-distance peripheral nerve injuries.
2 citations
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September 2023 in “International journal of molecular sciences” This review summarizes the roles of matricellular proteins in skin stem cell niches, highlighting their contribution to stem cell fate, self-renewal, and potential implications for wound healing and aging.
1 citations
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January 2020 in “Veterinariya Zootekhniya i Biotekhnologiya” This study observed that in long-haired cat breeds, there is an inverse relationship between epidermis thickness and hair cover thickness, regardless of breed.
January 2019 in “Durham e-Theses (Durham University)” This study found that JNK plays a dominant role in hair follicle matrix density-dependent proliferation and differentiation, suggesting that collagen bundling affects keratinocyte dynamics.
9 citations
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October 1976 in “Journal of Cutaneous Pathology” This study observed that human growth hormone treatment in osteoporosis patients appeared to improve skin thickness and restore dermal structures towards normal without stimulating hair, sebum, or melanin.
7 citations
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January 2021 in “Evidence-based complementary and alternative medicine” This study suggests that porphyra-334 may have antiaging properties, promoting collagen synthesis, improving periorbital wrinkles, and supporting hair follicle growth through gene regulation.
5 citations
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September 2017 in “PubMed” This study found that hypothermically stored amniotic membrane grafts promoted greater tissue regeneration, including basket-weave collagen matrix and follicle formation, compared to dehydrated amnion/chorion meshed grafts in a rat wound model.
2 citations
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May 2023 in “Frontiers in Bioengineering and Biotechnology” This review explores the potential of multifunctional bioscaffolds in skin tissue engineering, highlighting their successful biological performance in vitro and in vivo animal models, while also identifying the demand for technological advancements to improve wound healing applications in clinical settings.
1 citations
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December 2015 in “The Egyptian Journal of Histology” This study found that experimentally induced hypothyroidism in rats is associated with impaired skin structure, but topical application of triiodothyronine (T3) improved these changes to resemble normal skin.
October 2025 in “Journal of the Endocrine Society” This research review observed that topical hormone replacement therapy, particularly estradiol and estradiol-testosterone combinations, significantly increased Type I and III collagen synthesis in the skin of postmenopausal women, suggesting benefits against collagen loss-related skin aging effects such as reduced elasticity and increased dryness.
June 2023 in “Research Square (Research Square)” This study found that polycaprolactone (PCL) in facial fillers led to more cell proliferation and vascular activity than hyaluronic acid (HA) in Wistar rats, suggesting enhanced tissue regeneration effects with PCL.
October 2021 in “Journal of Investigative Dermatology” This study found that fibroblasts from mature skin showed significantly reduced mechanical force production compared to young skin fibroblasts, suggesting age-related changes in cellular mechanical properties.
January 2019 in “The Review of Laser Engineering” This study observed that multiphoton excitation microscopy revealed changes in vascular structure and hair papillae in mice subcutaneous tissue following cyclophosphamide treatment for chemotherapy-induced alopecia.
January 2012 in “RWTH Publications (RWTH Aachen)” This study found that patient-derived HGF significantly accelerates wound healing in diabetic mice, particularly improving skin structure and flexibility, and rHGF plays a key role in boosting hair growth.
February 2024 in “Australasian journal of dermatology” This study found that in atrophic acne scars, inflammation infiltrates the pilosebaceous unit over time, affecting resident stem cells and hindering the normal regeneration of the epidermis and adnexal structures, leading to scarring.
September 2001 in “Dermatologic Surgery” This review derived guidelines for scalp surgery suggesting improved outcomes when avoiding neurovascular structures, preserving tissue integrity, and maintaining hair direction, but it reports no new clinical results.
47 citations
,
April 1978 in “Journal of Cutaneous Pathology” This study found that basal cell epithelioma resembles fetal primary epithelial germ based on specific cellular characteristics.
22 citations
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February 2023 in “Heliyon” This study reports that a heparin-based sericin hydrogel encapsulating basic fibroblast growth factor significantly accelerated wound healing in mice by enhancing vascularization, re-epithelialization, and collagen deposition.
2 citations
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December 2024 in “Microscopy Research and Technique” This study introduced a novel microscopy system using an Er3 + −doped femtosecond fiber laser, achieving detailed imaging of biological structures in plant and skin samples with improved spatial resolution for various applications, including in vivo imaging.
1 citations
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April 2023 in “Scientific Reports” This study reported that newly developed RADA16-I peptide hybrids, with active motifs like GHK and KGHK, demonstrated improved wound healing in a mouse skin injury model without cytotoxicity, suggesting they might be effective scaffolds for tissue engineering and regeneration.
October 2024 in “Acta Biomaterialia” This study introduced a novel method that uses upright structured illumination microscopy and atomic force microscopy to map the mechanical properties of thick living tissue slices, revealing the intricate mechanical heterogeneity of mouse skin and effects of preservation techniques on tissue stiffness.
February 2026 in “Nano Research” In this study, researchers developed a near-infrared-responsive nanoplatform that synergistically enhances chronic wound healing by accelerating mitochondrial restoration and immune modulation, leading to enhanced wound repair and high-quality healing in diabetic rat models.
4 citations
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June 2022 in “Cold Spring Harbor Perspectives in Biology” This review discusses the heterogeneity of dermal fibroblasts in healthy mouse and human skin and reports no clinical results; the authors highlight potential insights into physiological and pathological wound healing.