Technical Advancement and Biomedical Application of Multiphoton Excitation Microscopy
January 2019
in “
The Review of Laser Engineering
”
TLDR Multiphoton excitation microscopy is a promising tool for deep tissue imaging and clinical applications.
The document discussed the use of multiphoton excitation microscopy as a promising technique for intravital imaging in biology and clinical medicine. This nonlinear optical phenomenon allowed for deep tissue analysis and label-free imaging of collagen. The study specifically used this technique to investigate chemotherapy-induced alopecia in mice, observing changes in vascular structure and hair papillae after treatment with cyclophosphamide. The advancements in this microscopy technique suggested its potential as a practical tool for both bioimaging analysis and future clinical applications.