1 citations
,
December 2023 in “Life” This article discusses the potential role of telocytes in skin regeneration and the need to understand their interaction with platelet-rich plasma, reporting no new experimental results.
1 citations
,
November 2021 in “Biomedicines” This review elaborates on the concept of cutaneous mosaicism and its link to acneiform conditions, but it reports no new clinical results.
This study investigated the effects of pathological α-synuclein on sebaceous gland cells in Parkinson's disease, finding that α-synuclein exposure altered cellular differentiation and lipid production, suggesting a potential link between α-synuclein and lipid dysregulation in the skin of PD patients.
June 2025 in “Cell Metabolism” This study found that dietary serine levels influence hair follicle stem cells' ability to balance hair regeneration and wound repair, offering insights for potential interventions to accelerate wound healing.
November 2021 in “International Journal for Research in Applied Science and Engineering Technology” This review discusses the various applications of lyophilized platelet-rich plasma in treating different diseases and reports no new clinical results.
37 citations
,
January 2002 in “British journal of dermatology/British journal of dermatology, Supplement” This study found that procyanidin B-2 may promote hair growth by reducing expression and inhibiting translocation of PKC isozymes in murine hair epithelial cells.
23 citations
,
December 2001 in “Lasers in Surgery and Medicine” This article discusses the extended theory of selective photothermolysis and does not report new clinical results; the authors explore potential applications in hair removal techniques.
1 citations
,
January 2015 in “Annals of Dermatology” This case report describes a 52-year-old woman who developed retiform purpura after using cocaine likely adulterated with levamisole, highlighting the need for levamisole detection in such cases.
72 citations
,
June 2001 in “Journal of Investigative Dermatology” This study suggests that S100A4 and S100A6 proteins may play key roles in activating stem cells for hair follicle regeneration in mice.
70 citations
,
July 2005 in “Journal of Ethnopharmacology” In this study, Ganoderma lucidum extract was found to significantly inhibit 5alpha-reductase activity and testosterone-induced prostate growth in rats, suggesting potential use for treating benign prostatic hyperplasia.
64 citations
,
March 2006 in “Food Chemistry” In castrated rats, this study found that triterpenoids from Ganoderma lucidum inhibited both types of 5α-reductase and reduced prostate growth linked to testosterone but not dihydrotestosterone.
27 citations
,
May 2006 in “Biochemical and Biophysical Research Communications” In this study, Wnt-10b was found to promote hair follicle development and hair growth in cultured mouse embryonic skin and transplanted skin in nude mice.
16 citations
,
September 2016 in “Neuropharmacology” This study suggests that in an ex vivo rat glaucoma model, TSPO activation is involved in Allopregnanolone synthesis and may help prevent retinal damage, with TSPO agonists as potential therapeutic agents.
11 citations
,
May 2015 in “Stem Cells Translational Medicine” This study found that megestrol acetate increases the proliferation, migration, and adipogenic differentiation of adipose-derived stem cells through glucocorticoid receptor phosphorylation.
10 citations
,
May 2018 in “Neuropharmacology” This study suggests that inhibitors of steroidogenic enzymes may have therapeutic potential for certain behavioral disorders linked to dopaminergic hyperfunction, despite concerns about their endocrine impacts.
10 citations
,
November 2015 in “Experimental Dermatology” The study observed that mRAGE expression is prevalent in keratinocytes of the healthy human epidermis and may regulate inflammation and apoptosis to maintain skin homeostasis rather than responding to aging processes.
8 citations
,
January 2020 in “Skin Pharmacology and Physiology” This article discusses the potential for topical caffeine as a natural alternative for treating androgenetic alopecia due to its ability to penetrate skin, but it reports no new clinical findings.
6 citations
,
April 2010 in “Journal of Dermatological Science” This study observed that downregulation of laminin-511 plays an important role in hair regression during the catagen stage in mice.
5 citations
,
January 2001 in “Advances in protein chemistry” This chapter reviews recent advances in 5α-reductase inhibitors for treating disorders mediated by dihydrotestosterone and reports no new clinical findings.
1 citations
,
April 2018 in “Revista da Sociedade Portuguesa de Dermatologia e Venereologia” This article reviews the prevalence, causes, and associated conditions of hidradenitis suppurativa, a chronic inflammatory skin disease, but reports no new clinical findings.
January 2026 in “Food Science and Human Wellness” This research examined krill oil's effects on benign prostatic hyperplasia and found that it inhibited the growth of prostate cells in vitro and reduced prostate size and weight in a BPH rat model, suggesting potential as a prophylactic or therapeutic agent for BPH.
January 2026 in “Food Science and Human Wellness” This study found that oral administration of Flammulina velutipes polysaccharide reduced tumor volume and improved survival in mice by modulating macrophage polarization and enhancing antitumor immune responses.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that using a commercially available IPL home-use device led to significant hair reduction and demonstrated long-term efficacy in maintaining hair reduction one year after treatment.
54 citations
,
April 2010 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” This review discusses 46,XY disorders of sex development caused by defects in androgen production and highlights the need for long-term care from experienced multidisciplinary teams, but it reports no new clinical findings.
33 citations
,
June 2017 in “Developmental Biology” This study found that local refinement of hair follicles into higher order patterns can occur without the core planar cell polarity system, but global alignment with body axes requires its function throughout development and regeneration.
32 citations
,
January 2000 in “Skin pharmacology and physiology” In this study, procyanidin B-2 and C-1 were found to promote hair growth by selectively inhibiting protein kinase C, supporting their potential use for hair-growing activity.
In this retrospective study, researchers found that baricitinib was effective for treating moderate to severe alopecia areata, with response rates in 24 patients comparable to existing real-world data, and no new safety concerns were identified.
This review discusses drug repositioning for cardiometabolic disorders and reports no new clinical findings; the authors emphasize its potential benefits, such as known safety profiles and reduced development costs compared to new drug development.
13 citations
,
January 2014 in “Postępy Dermatologii i Alergologii” This report describes four cases of patchy, non-scarring alopecia areata that spared gray hairs and affected only pigmented hairs.
4 citations
,
August 2013 in “Case reports in dermatology” This case report describes a patient in whom vitiligo was induced by diphenylcyclopropenone treatment for alopecia universalis, highlighting the potential overlap of susceptibility genes between the two conditions.