This study concluded that combining letrozole with cabergoline improved ovulation and clinical pregnancy rates in patients with polycystic ovarian syndrome and hyperprolactinemia compared to letrozole alone.
January 2012 in “Medical Journal of Babylon” January 2026 in “Journal of Education Health and Sport” This review assesses whether using letrozole alongside physical activity and nutrition is clinically beneficial for enhancing ovulation outcomes in women with PCOS-related infertility, but it doesn't report specific results from the evaluation.
January 2011 in “Yearbook of Endocrinology”
2 citations
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February 2022 in “Frontiers in Endocrinology” This study found that antiandrogenic pretreatment with combined oral contraceptives did not improve ovulation and pregnancy outcomes compared to direct letrozole induction in women with PCOS.
March 2018 in “Chin J Reprod Contracep” This review outlines chlormadinone acetate's contraceptive and non-contraceptive applications but reports no new clinical findings, emphasizing its potential in treating dysmenorrhea and androgen-related conditions.
1 citations
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December 1971 in “PubMed” 62 citations
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December 1995 in “The Journal of Clinical Endocrinology & Metabolism” This study found that combining a GnRH agonist with a low-dose oral contraceptive was more effective in treating hirsutism than either agent alone and prevented hypoestrogenic side effects.
June 2026 in “International Journal of Innovative Technologies in Social Science” This source describes clascoterone, a new topical treatment for acne vulgaris that blocks androgen receptors to reduce sebaceous gland activity and inflammation, offering a lower risk of systemic side effects compared to oral treatments.
The authors concluded that capecitabine and high-dose toremifene may be an effective treatment option for patients unable to undergo anthracycline or taxane therapies, based on one woman's cancer management.
116 citations
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December 2013 in “European journal of endocrinology” This study found that combining liraglutide with metformin led to greater weight loss and waist circumference reduction than either treatment alone in obese women with PCOS resistant to metformin monotherapy.
74 citations
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January 2006 in “Endocrine journal” Low-dose gonadotropin treatment is effective for infertility in women with PCOS, leading to high ovulation rates and comparable pregnancy rates with fewer complications.
38 citations
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June 2004 in “Human Reproduction” This review discusses the challenges of using surrogate variables versus primary clinical end-points in PCOS trials and reports no new research results; the authors suggest focusing future studies on primary outcomes.
27 citations
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March 2018 in “Fertility and Sterility” This study found that in Chinese women with PCOS, pretreatment with ethinylestradiol/cyproterone acetate was associated with a lower risk of gestational diabetes, pregnancy-induced hypertension, and premature delivery compared to those without pretreatment.
19 citations
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October 2018 in “Medicine” In this meta-analysis, researchers found that moxibustion combined with oriental herbal medicine may improve pregnancy rates and other outcomes in women with polycystic ovary syndrome compared to western medication alone; however, the evidence is limited by the poor quality of included studies.
11 citations
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March 2016 in “Translational Andrology and Urology” This review highlights the potential therapeutic applications of nandrolone, an anabolic steroid, for male health, but notes that more human studies are needed due to limited existing literature.
10 citations
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September 2015 in “Gynecological Endocrinology” In this study, spironolactone and spironolactone plus metformin both significantly reduced hirsutism scores in women with PCOS, but the combination therapy was not more effective than spironolactone alone regarding BMI, hormone levels, or insulin resistance.
8 citations
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June 2017 in “Hormone Molecular Biology and Clinical Investigation” This study found that subclinical hypothyroidism had minimal impact on the metabolic and hormonal profiles of women with polycystic ovary syndrome.
3 citations
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October 1988 in “Clinics in Dermatology” This study found that 3% topical minoxidil decreased hair shedding and promoted hair growth in women with androgenetic alopecia.
2 citations
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December 1994 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study concluded that a regimen of transdermal estradiol and oral medroxyprogesterone acetate effectively reduces hirsutism while minimizing side effects in women with polycystic ovary syndrome.
1 citations
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March 2022 in “International Journal of Nutrology” This study found that myo-inositol improved fertility and metabolic parameters in women with polycystic ovary syndrome, including those undergoing in vitro fertilization, and reduced the risk of gestational diabetes.
1 citations
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December 2015 in “Endocrinology” This study suggests that dietary decanoic acid may manage hyperandrogenism and insulin resistance in PCOS, as observed in animal and cell model experiments.
1 citations
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January 2015 in “Case reports in endocrinology” This case report highlights that women with nonclassical congenital adrenal hyperplasia should be aware of the risk of having a child with classical CAH if their partner also carries a severe mutation.
1 citations
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August 2013 in “Fertility and Sterility” Finasteride may improve sperm count in subfertile men with low sperm count.
February 2026 in “International Journal on Science and Technology” This review discusses the potential benefits of Vitex negundo for managing polycystic ovarian disease, highlighting its promising effects in animal models, but notes that more rigorous human trials are needed to confirm these findings.
February 2025 in “Cureus” This case report describes a 37-year-old female with non-classical congenital adrenal hyperplasia who presented with severe acne, progressive hair loss, and primary infertility, managed with prednisolone.
March 2024 in “International journal of life-sciences scientific research/SSR Institute of International Journal of Life Sciences” This systematic review reported that PCOS is marked by increased androgens, hirsutism, and an elevated LH/FSH ratio, with metformin showing a therapeutic effect on menstrual cycles, emphasizing the need for individualized treatment strategies.
August 2023 in “International journal of reproduction, contraception, obstetrics and gynecology” This study found that combining letrozole with metformin was more effective at inducing pregnancy in women with PCOS compared to letrozole alone, while OCP and metformin significantly improved menstrual regularity and reduced hyperandrogenic symptoms.
This review discusses the diagnosis, symptoms, and treatment options for polycystic ovary syndrome but reports no new research findings; the authors emphasize the importance of early diagnosis and treatment to reduce complications.
This study found that resveratrol improved ovarian function, menstrual irregularities, hair loss, and sex hormone levels in patients with polycystic ovary syndrome compared to placebo.