7 citations
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January 2015 in “Case reports in endocrinology” This case report indicates that HAIR-AN syndrome can lead to severe hyperandrogenism with virilisation signs in women after excluding tumoral causes and identifying signs of insulin resistance.
51 citations
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August 2012 in “Differentiation” This study found that penile and clitoral differentiation in mice is influenced by androgen exposure, with penile features developing postnatally requiring prenatal and ongoing androgen presence.
9 citations
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January 2007 in “Endocrine Practice” This case report describes a 60-year-old postmenopausal woman with virilization and hirsutism caused by hilus-cell hyperplasia, which was confirmed following bilateral salpingo-oophorectomy.
This case report describes a six-year-old girl with hypertrichosis cubiti, characterized by excess terminal hair growth around the elbows, and notes treatment with over-the-counter depilatory creams and shaving to address aesthetic concerns.
September 2018 in “Gynecology & Obstetrics” In a meta-analysis of 210 hair tourniquet syndrome cases, this study reported that 44.2% involved the penis, 40.4% the toes, and 8.6% fingers, highlighting the condition's potential severity and underreporting, especially in infants and some adults with cognitive impairments.
1 citations
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August 2021 in “Pediatrics in review” This case report describes a rare instance of labial hair tourniquet syndrome in a 10-year-old girl, emphasizing the importance of considering this condition in the differential diagnosis of vulvar lesions.
1 citations
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February 2022 in “Case reports in endocrinology” This case report describes a 64-year-old postmenopausal woman with hirsutism due to a rare case of bilateral diffuse ovarian Leydig cell hyperplasia, leading to normalized testosterone levels and improved glycaemic control following surgery.
42 citations
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January 2003 in “International Journal of Gynecological Pathology” This research observed that multifocal pseudoepitheliomatous hyperplasia may explain some cases of squamous nests in vulvar lichen sclerosus with lichen simplex chronicus, potentially as a reaction to tissue damage rather than squamous cell carcinoma.
December 2021 in “Aegean journal of obstetrics and gynecology” This case report highlights a rare instance of postmenopausal virilization in a 71-year-old woman due to coexisting ovarian hilus cell hyperplasia and a Sertoli-Leydig cell tumor.
May 2024 in “Indian Dermatology Online Journal” This study reports a case of trichobacteriosis pubis, a rare bacterial infection causing malodour in the pubic region, which improved with hair trimming and topical clindamycin, subsequently enhancing the patient's sexual relationship.
This study reports isolated clitoral hood hair-thread tourniquet syndrome, highlighting the importance of suspicion in females with prominent clitoral hood and genital pain to facilitate timely intervention and tissue preservation.
April 2020 in “Journal of the Endocrine Society” This case report details a post-menopausal woman with hirsutism and virilization due to rare Leydig cell tumors in both ovaries, underscoring the challenge of detecting such tumors with standard imaging.
January 2022 in “International Microsurgery Journal” In this case report, the authors described how a 27-year-old male developed scarring and penile shortening after a previous lengthening procedure, which was successfully repaired using a pedicled superficial circumflex iliac artery perforator flap combined with a novel hybrid technique.
January 2023 in “The Annals of african surgery” This review concludes that preoperative hormonal stimulation with testosterone or DHT may help increase penile length and glans circumference, easing hypospadias surgery and potentially reducing postoperative complications.
5 citations
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July 2005 in “British journal of dermatology/British journal of dermatology, Supplement” This case study reports an unusual occurrence of hair growth on the glans penis of a healthy 24-year-old man, which required surgical excision but recurred at a different site.
1 citations
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January 2018 in “Journal of SAFOMS” This case report describes a postmenopausal woman with a rare instance of ovarian fibrothecoma exhibiting virilizing features, who presented with symptoms such as excess hair growth and clitoromegaly.
12 citations
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June 1999 in “Dermatologic Surgery” In this study, hair restoration surgery using mini-micrograft techniques successfully improved aesthetic outcomes and patient satisfaction in women with hypotrichosis of the pubis, particularly when preoperative evaluation matched pubic hair design to individual patient preferences.
11 citations
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February 1980 in “BMJ. British medical journal” This article reviews hirsutism, its causes, cultural perceptions, and symptoms, but provides no new clinical findings beyond existing descriptions and statistics on hair growth patterns in women.
October 1984 in “Kidney international” This case report describes a 23-year-old woman with a history of ambiguous genitalia and complex medical conditions, including a pelvic mass and hirsutism, observed from childhood to adulthood.
October 2022 in “Miscellaneous” This study documented a case of a 57-year-old woman with postmenopausal virilism due to a Sertoli-Leydig cell tumor, which improved after surgical treatment.
2 citations
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October 2015 in “Obstetrics and gynaecology cases - reviews” This case report details a postmenopausal woman with increased libido, hirsutism, and spontaneous orgasms, noting elevated testosterone levels and enlarged ovaries.
March 2016 in “Journal of the Turkish-German Gynecological Association” The woman likely has a hormonal imbalance causing excessive hair growth.
In this case report, a 10-year-old girl with an adrenal adenoma experienced symptoms like hirsutism and clitoromegaly; after surgical removal of the tumor, her symptoms and biochemical abnormalities resolved over several months.
2 citations
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June 2012 in “American Journal of Dermatopathology” This case study describes a rare cutaneous follicular hybrid cyst intimately associated with syringocystadenoma papilliferum, proposing a potential relationship with the infrainfundibulum based on keratin expression.
January 2025 in “Haematology International Journal” This study describes a functional disorder in the ovary, known as stromal hyperplasia, characterized by the proliferation of ovarian stroma and luteinization of stromal cells, which is linked to excessive androgen production and elevated testosterone levels.
April 2020 in “Journal of the Endocrine Society” This case report highlights Leydig cell hyperplasia as a rare cause of increased testosterone and postmenopausal hirsutism, resolved after bilateral salpingo-oophorectomy in a 64-year-old woman.
7 citations
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August 2012 in “The Journal of Urology” This study found that despite androgen excess and genitourinary masculinization, adult women with congenital adrenal hyperplasia did not exhibit notable prostatic growth.
27 citations
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June 1989 in “Journal of Medical Genetics” This case report describes four patients with hypertrichosis cubiti and short stature, but could not determine a genetic link between hypertrichosis cubiti and skeletal dysplasia.
September 2024 in “Pediatrics in Review” In this case review, researchers describe a 17-year-old transgender male experiencing clitoromegaly, hirsutism, and oligomenorrhea, investigating conditions like PCOS and non-prescription testosterone use for gender affirmation, and highlighting the importance of gender-affirming care to improve mental health outcomes.
September 2024 in “Medicine theory and practice” In a clinical case study, researchers identified adrenocortical adenoma as the cause of hyperandrogenism syndrome in a preschool-aged girl, following a comprehensive diagnostic process and successful surgical intervention to remove the tumor, leading to positive clinical improvements.