Absence of Prostatic Growth in a Large Cohort of Adult Female Patients with Congenital Adrenal Hyperplasia

The study investigated the presence of prostatic tissue in 43 adult women with congenital adrenal hyperplasia, focusing on 11 who underwent detailed examinations. Despite androgen excess and genitourinary masculinization, the study found no significant prostatic growth in these patients. Only one patient showed periurethral thickening, and another had a slightly elevated prostate-specific antigen level, but magnetic resonance imaging confirmed the absence of definitive prostatic tissue in all participants. The findings suggested that, contrary to some case reports, notable prostatic growth was absent in these women, highlighting the need for further research to understand the factors influencing prostatic growth in this population.