October 2023 in “BMC endocrine disorders” In this case study, researchers observed a 5.8-year-old male with peripheral precocious puberty due to a germ cell tumor, marked by elevated human chorionic gonadotropin levels. Treatment normalized hormone levels and arrested the puberty progression, highlighting melatonin's potential role in transitions to central precocious puberty.
24 citations
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October 2017 in “Scientific reports” This study suggests that controlling light exposure can influence cashmere growth by triggering hair follicles to enter their active growth phase sooner, potentially involving the CSDC2 gene as a key regulator.
2 citations
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October 2016 in “European Neuropsychopharmacology” June 2008 in “Experimental Dermatology” This study suggests that combining 17-beta estradiol with prednisolone could accelerate hair regrowth after chemotherapy-induced alopecia in humans, based on preclinical findings using an in vitro model.
57 citations
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September 2006 in “Cancer Nursing” This descriptive study reported that adults undergoing chemotherapy or radiation therapy experienced severe symptoms like fatigue and constipation, with nutrition changes being a common self-care strategy.
August 2023 in “Clinical Endocrinology and Metabolism” This article provides evidence on when it is appropriate to prescribe hormone therapy for women by reviewing cases from the author's practice and international literature, emphasizing the importance of primary care in managing hormonal imbalances.
September 2026 in “European Journal Pharmaceutical and Medical Research” This source discusses premature greying of hair, often linked to lifestyle, stress, and nutritional deficiencies, and notes mainstream dermatology focuses on dietary supplements, while homeopathy offers a holistic approach for treatment.
1 citations
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January 2011 in “Journal of the American Academy of Dermatology” The combination of minoxidil and cyclosporine improved hair growth in short anagen syndrome.
This abstract introduces TrichoFoam™, a new foaming vehicle for compounding pharmacies, designed to be a gentle, non-irritating option for alopecia treatment, acknowledging that current topical treatments are limited and oral products may cause adverse effects.
5 citations
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August 2014 in “Dermatologic surgery” Advanced fluorescence technology effectively treats skin discoloration from certain creams.
January 2017 in “Chemistry & Industry” Eating fewer calories may slow aging and removing old cells can increase lifespan in mice.
10 citations
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January 2017 in “Skin appendage disorders” This case study reports the first documentation of the intermittent nature of chronic telogen effluvium and suggests a link between emotional stress and hair shedding severity.
This review discusses various management methods for adolescents with PCOS, highlighting lifestyle modifications and pharmaceuticals like metformin and oral contraceptives, but reports no new clinical results; the authors emphasize individualized treatment plans.
6 citations
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April 2012 in “PubMed” This case report describes a 33-year-old Indian male with Cronkhite-Canada syndrome who experienced complete symptom recovery within 5 months after starting a high protein diet, proton pump inhibitors, and zinc-vitamin supplements.
99 citations
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September 2007 in “The American journal of pathology” This study found that organ-cultured human scalp hair follicles can mimic chemotherapy-induced damage in vivo and serve as a model to explore molecular targets and protective agents for hair follicle preservation.
November 2022 in “Journal of Investigative Dermatology” This study found that Cyclosporin A may prolong the anagen phase of hair growth in cultured dermal papilla cells by decreasing TGF-β2 expression, similar to its mechanism in immunosuppression.
13 citations
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December 2017 in “Stem cells” This study found that in mice, low-dose irradiation causes stem cells in hair follicles to undergo chromatin alterations, which may eventually lead to long-term functional loss in tissues or organs.
9 citations
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January 1983 in “Journal of Chromatography B Biomedical Sciences and Applications” This study found that enzyme activity related to cancer induction by polycyclic aromatic hydrocarbons can be increased by using a shampoo containing crude coal tar and significantly inhibited by imidazole compounds in human hair follicles.
December 2023 in “Trials” In this randomized controlled trial involving breast cancer patients undergoing chemotherapy, this study investigated the efficacy of low-level light therapy for preventing hair loss, measuring outcomes like hair count and patient quality of life, but the abstract does not report specific results.
May 2026 in “Актуальні питання педіатрії акушерства та гінекології” In this study of young women with menstrual cycle disorders, researchers found that the type and severity of skin conditions are linked to both androgen levels and local skin receptor expression, suggesting customized treatment strategies could enhance management.
12 citations
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August 2020 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This study found that most chronic alopecia areata patients treated with azathioprine, methotrexate, or cyclosporine continued treatment for at least 12 months, often requiring concurrent low-dose prednisolone.
5 citations
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April 2024 in “ACS Chemical Neuroscience” This study developed and validated a highly sensitive method using ultrahigh-performance liquid chromatography with tandem mass spectrometry for accurately analyzing nine neuroactive steroids in human serum, which could enhance understanding of disease pathophysiology and support new biomarker and therapeutic discovery.
January 2024 in “Indian Journal of Pharmacy Practice” This study examined 142 patients with subclinical thyroid disorders and found a high incidence of comorbidities like renal diseases. Researchers reported that good medication adherence was associated with better quality of life, indicating a significant relationship between adherence and quality of life.
9 citations
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November 2013 in “BMC Pharmacology and Toxicology” This study found that transient inhibition of eIF4E in a transgenic mouse model protected against cyclophosphamide-induced hair loss by inducing cell cycle arrest and reducing cellular apoptosis.
July 2022 in “British Journal of Dermatology” August 2026 in “PLoS ONE” This study will evaluate the clinical efficacy, patient-reported outcomes, and economic impact of the PAXMAN® PSCS 2 automated scalp cooling system versus standard cold-cap therapy to prevent chemotherapy-induced hair loss in women with localized breast cancer during anthracycline and taxane treatment.
5 citations
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February 2016 in “International Journal of Cancer” In this mouse study, applying a vasoconstrictor before chemotherapy did not create a leukemia sanctuary or significantly impact survival outcomes, suggesting it may not interfere with leukemia treatment.
8 citations
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January 2016 in “Journal of Investigative Dermatology” This review discusses the use of the human-on-mouse xenograft model for studying the human hair follicle cycle and emphasizes its utility for pharmacological testing, without reporting new clinical results.
February 2024 in “Scientific Reports” In this retrospective cohort study, 87.1% of pediatric patients with chemotherapy-induced alopecia experienced clinical improvement after treatment with minoxidil or combination therapy with CYP, with the combination therapy showing greater hair thickness and minimal adverse effects.