Case of Cronkhite-Canada Syndrome Shows Improvement with Enteral Supplements

Cronkhite-Canada syndrome (CCS) is a rare condition with only about 450 cases reported worldwide. This case study involved a 33-year-old Indian male who presented with symptoms including loose stools, abdominal pain, weight loss, generalized weakness, significant hair loss, and hyperpigmentation. Further symptoms included hypogeusia and onychodystrophy. Endoscopic examination revealed severe gastroduodenitis and multiple polyps, with biopsies showing eosinophilic gastritis and hamartomatous polyps. Treatment with high protein supplements, proton pump inhibitors, and zinc-vitamin supplements led to complete recovery within 5 months. Early diagnosis and appropriate treatment were crucial for symptom improvement in this rare disease.