A Case of Cronkhite-Canada Syndrome with Telogen Effluvium and Onycholysis

A 53-year-old male patient was diagnosed with Cronkhite-Canada Syndrome (CCS) after experiencing symptoms such as tongue pain, diarrhea, and hair loss. The hair loss was characterized by multiple areas of sparse hair on the scalp, and a positive pull test indicated telogen effluvium. A scalp biopsy showed all hair follicles in the telogen phase without inflammatory cell infiltration. Gastrointestinal endoscopy revealed small polyps with redness from the ileum to the rectum. Treatment with 30 mg/day of prednisolone improved diarrhea and hair regrowth, and after tapering the medication, symptoms did not recur. One year later, follow-up endoscopy showed all polyps had disappeared. While CCS-related hair loss has traditionally been considered telogen effluvium, recent reports suggest it may be linked to Alopecia areata incognita (AAI), which could also apply to this case.