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Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Adrenal disorders can cause lasting brain and behavior issues in children.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Accurate clinical, histological, and genetic methods are key for understanding and treating hair disorders.

Trichoscopy is a useful tool for diagnosing hair disorders without pulling out hair.

Eating glucoraphanin can help prevent psychosis in offspring whose mothers had immune system activation.

Cells from a skin condition can create new hair follicles and similar growths in mice, and a specific treatment can reduce these effects.

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.

Mice with enhanced regeneration abilities may help develop new regenerative medicine therapies.

Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.

High androgen levels and genetic factors likely cause Becker's nevus and related symptoms.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

The gene p53 is crucial for removing damaged cells to allow for healthy tissue renewal.

Gata6 is important for protecting hair growth cells from DNA damage and keeping normal hair growth.

The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.

Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.

Obesity worsens Polycystic Ovary Syndrome symptoms, and weight loss is a key treatment.

Early recognition and management of skin side effects from new cancer therapies can prevent treatment delays.

Certain gene variations are not a major cause of male infertility in Nigerian men.

Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.

GasderminA3 is important for normal hair cycle transitions by controlling Wnt signaling.

Different processes create patterns in skin and things like hair and feathers.

CRTH2 antagonists might be useful for treating many conditions because they play a role in immune and inflammation responses.

Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

St. John's Wort extract and oil safety in cosmetics is unclear; more data needed on photosensitization, toxicity, and human irritation.

Understanding hair follicle biology and stem cell control could lead to new hair loss treatments.