research Antagonism of NMDA Receptors as a Potential Treatment for Down Syndrome: A Pilot Randomized Controlled Trial
Memantine may slightly improve memory in people with Down syndrome, but more research is needed.
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research A Position Effect on TRPS1 Is Associated with Ambras Syndrome in Humans and the Koala Phenotype in Mice
A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.
research Innovative Use of Spironolactone as an Antiandrogen in the Treatment of Female Pattern Hair Loss
Spironolactone helps regrow hair in women with hair loss.
research The Hairless Gene of the Mouse: Relationship of Phenotypic Effects with Expression Profile and Genotype
Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.
research Hair Removal With Intense Pulsed Light
Intense pulsed light (IPL) is an efficient and safe method for hair removal, reducing hair by about 80%.
research Mutations in the Keratin 85 (KRT85/hHb5) Gene Underlie Pure Hair and Nail Ectodermal Dysplasia
Mutations in the KRT85 gene cause hair and nail problems.
research Genotype-Phenotype Correlation in Boys with X-Linked Hypohidrotic Ectodermal Dysplasia
Boys with less severe EDA mutations in XLHED have milder symptoms and better sweat and hair production.
research Comparison of Rheological Properties, Follicular Penetration, Drug Release, and Permeation Behavior of a Novel Topical Drug Delivery System and a Conventional Cream
The new drug delivery system releases the drug better in sebum and targets follicles more effectively than the conventional cream.
research Unique Cutaneous Reaction to Second- and Third-Generation Tyrosine Kinase Inhibitors for Chronic Myeloid Leukemia
Certain leukemia drugs can cause severe skin reactions that may require stopping treatment.
research Green Synthesis of Silver Nanoparticles Using Grewia Optiva Leaf Aqueous Extract and Isolated Compounds as Reducing Agent and Their Biological Activities
Silver nanoparticles made from Grewia optiva leaf extract show strong antibacterial, antioxidant, and hair growth benefits.
research Characterization of X-Linked SNP Genotypic Variation in Globally Distributed Human Populations
The research concluded that selection significantly shaped the genetic variation of the X chromosome, with certain regions affected by past selective events.
research Metabolism of Minoxidil, a New Hypotensive Agent: Biotransformation Following Oral Administration to Rats, Dogs, and Monkeys
Minoxidil metabolizes similarly in monkeys and humans, but differently in dogs and rats.
research Determination of Finasteride in Human Plasma by Liquid-Liquid Extraction and High-Performance Liquid Chromatography
Valid method measures finasteride in plasma, simple, fast, and affordable.
research Hair Removal Using a Pulsed-Intense Light Source
Pulsed-intense light can significantly reduce hair, with effectiveness depending on treatment number and timing, and has mild side effects.
research Hair Growth Stimulatory Effect by a Combination of 5-Aminolevulinic Acid and Iron Ion
A mix of 5-aminolevulinic acid and iron ion can speed up hair growth.
research A Perspective on the Evolving Landscape in Male Reproductive Medicine
Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.
research Rapid Determination of Finasteride in Human Plasma by UPLC-MS/MS and Its Application to Clinical Pharmacokinetic Study
New method measures finasteride in blood quickly and accurately.
research Genetics of Structural Hair Disorders
The document concludes that over 500 genes are linked to hair disorders and this knowledge is important for creating new treatments.
research Finasteride in Biological Fluids: Extraction and Separation by a Graphitized Carbon Black Cartridge and Quantification by High-Performance Liquid Chromatography
Method accurately measures finasteride in human plasma.
![Distribution of 1,25-Dihydroxyvitamin D3[22-Oxa] In Vivo Receptor Binding in Adult and Developing Skin](/images/research/d9b990e6-6243-4abe-b868-68801a5844f7/small/35023.jpg)
research Distribution of 1,25-Dihydroxyvitamin D3[22-Oxa] In Vivo Receptor Binding in Adult and Developing Skin
OCT binds strongly to hair sheath cells and may affect skin and hair growth with fewer side effects than vitamin D3.
research Marie Unna Hereditary Hypotrichosis Caused by a Novel Mutation in the Human Hairless Transcript
A new mutation in the HR gene causes hair loss in a specific family.
research Pericardial Effusions Associated with Minoxidil
research Separation of Finasteride and Analogues
Finasteride and analogues separated using LC-MS-MS technique.
research Androgen Receptor Polymorphism-Dependent Variation in Prostate-Specific Antigen Concentrations of European Men
Certain genetic variants in the androgen receptor are linked to higher PSA levels, potentially affecting prostate cancer screening outcomes.
research The Hair Growing Effect of Minoxidil
Minoxidil helps hair growth by increasing blood flow and stimulating hair follicles.
research Determination of Finasteride and Related Compounds by Reversed-Phase High Performance Liquid Chromatography: Choosing the Mobile Phase Composition
Best results found using acetonitrile, water, and trifluoroacetic acid or methanol mixture.
research Pharmacological Inhibition of DGAT1 Induces Sebaceous Gland Atrophy in Mouse and Dog Skin While Overt Alopecia Is Restricted to the Mouse
Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.
research Bioequivalence Study of Finasteride
Finasteride's two formulations absorb similarly, showing bioequivalence.
research Increased Retinol-Binding Protein 4 and Anti-RBP4 Antibody in Alopecia Areata
People with alopecia areata have higher levels of RBP4 protein and antibodies against it.
research Simultaneous Determination of Minoxidil and Minoxidil Sulfate by High-Performance Liquid Chromatography with UV Detection and Its Applications
The study developed a method to detect minoxidil and its sulfate form, found that minoxidil sulfate is temperature-sensitive, and identified a way to potentially increase its stability for hair loss treatment.