research Investigation of Transfollicular Caffeine Penetration Using Microdialysis on Ex Vivo Porcine Ear Skin
Caffeine penetrates skin quickly through open hair follicles, but less through closed ones, with levels becoming equal after 22 hours.
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research The Peptide AC 2 Isolated from Bacillus-Treated Trapa Japonica Fruit Extract Rescues DHT-Treated Human Dermal Papilla Cells and Mediates mTORC1 Signaling for Autophagy and Apoptosis Suppression
The AC 2 peptide from Trapa japonica fruit helps protect hair cells and may treat hair loss.
research Green Synthesis of Silver Nanoparticles Using Grewia Optiva Leaf Aqueous Extract and Isolated Compounds as Reducing Agent and Their Biological Activities
Silver nanoparticles made from Grewia optiva leaf extract show strong antibacterial, antioxidant, and hair growth benefits.
research Preparation of Finasteride Capsules-Loaded Drug Nanoparticles: Formulation, Optimization, In Vitro, and Pharmacokinetic Evaluation
Finasteride capsules with nanoparticles improve drug delivery, solubility, stability, and effectiveness.
research Exogenous and Endogenous Lipids of Human Hair
Removing external lipids from hair reduces moisture and increases strength, while removing internal lipids decreases water permeability.
research The Proteomic Profile of Hair Damage
Bleaching hair damages protein structure, especially keratin, leading to weakened hair.
research Distribution of Glycolipid and Unsaturated Fatty Acids in Human Hair
Human hair has more unsaturated fats inside than on the surface, and certain lipids may help bind the outer and inner layers together.
research Non-Invasive Approaches for the Diagnosis of Autoimmune/Autoinflammatory Skin Diseases: A Focus on Psoriasis and Lupus Erythematosus
Non-invasive methods show promise for diagnosing skin diseases like psoriasis and lupus but need more research for regular use.
research The Role of 3Rs in the Age of One Health: Where We Are and Where We’re Going
Innovative methods are reducing animal testing and improving biomedical research.
research Structural and Functional Studies of L-PGDS and SMPDL3A Enzymes in Lipid Signaling Family
L-PGDS has specific binding sites for its functions and could help in drug delivery system design.
research Chemical Examination of Three Indian Medicinal Plants and Their Hair Growth Evaluation Studies
Three Indian medicinal plant compounds help hair growth.
research Testosterone and Doping Control
The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.
research Human Hair Follicle: Reservoir Function and Selective Targeting
The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.
research Androgen Excess: Investigations and Management
The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.
research Animal Models for the Study of Fetal Tissue Repair
Understanding how fetal wounds heal could help improve healing in adults.
research Engineering Cell-Derived Matrices: From 3D Models to Advanced Personalized Therapies
3D cell-derived matrices improve tissue regeneration and disease modeling.
research Predominant Expression of 5 Alpha-Reductase Type 1 in Pubic Skin from Normal Subjects and Hirsute Patients
The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.
research Female Hyperandrogenism
The document concludes that managing female hyperandrogenism requires a combination of identifying the cause, lifestyle changes, medication, and cosmetic treatments.
research Development and Evaluation of Crystalline Inclusion Complex of Finasteride Using Electrospraying as a Novel Approach
Created finasteride complex to increase water solubility and drug release.
research The Laboratory in the Multidisciplinary Diagnosis of Differences or Disorders of Sex Development (DSD)
Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.
research Hair and Scalp Variation Related to Gender
Gender affects hair and scalp characteristics, with differences in hormone responses, graying patterns, and trace metals.
research Management of Endocrine Disease: Hyperandrogenic States in Women - Pitfalls in Laboratory Diagnosis
Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.
research The Therapeutic Role of ADSC-EVs in Skin Regeneration
ADSC-derived extracellular vesicles show promise for skin and hair regeneration and wound healing.
research A Large Benign Adrenocortical Adenoma Cosecreting Testosterone and Cortisol
A woman's rare benign tumor that released both cortisol and testosterone was successfully removed, improving her health.
research Non-Classic Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency Revisited: An Update with a Special Focus on Adolescent and Adult Women
The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.
research GC-MS Profiling and In Silico Prediction of MAPK Receptor Activation by Fatty Acids of Watercress Oil for Hair Growth Marketed in Saudi Arabia
Watercress oil may promote hair growth by activating specific receptors.
research Omics for Precious Rare Biosamples: Characterization of Ancient Human Hair by a Proteomic Approach
The study developed a method to analyze ancient hair proteins using very small samples.
research In Vitro and In Silico Evaluation of Toxicological and Anti-Proliferative Activity in Phytochemical Compounds of Several Solvent Extracts from Zaleya Pentandra L
Zaleya pentandra extracts, especially acetone, may be useful for new medicines and food industry applications.
research Anti-Doping Testing at FIFA World Cup 2022
All samples tested negative for banned substances, ensuring competition integrity.
research Phytochemical Profiling and Evaluation of the Anti-Aging and Anti-Inflammatory Potential of Cultivated Eclipta Alba (L.)
Eclipta alba has anti-aging and anti-inflammatory properties, making it a potential ingredient for cosmetics.