August 2015 in “Dermatología Argentina” This study reviewed 18 postmenopausal women with frontal fibrosing alopecia, noting frontotemporal hairline recession and eyebrow loss, often treated with steroids, triamcinolone, and other medications.
24 citations
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September 2015 in “JAAD case reports” This case report describes a patient with frontal fibrosing alopecia experiencing significant hair regrowth and reversal of cutaneous atrophy after treatment with the 5α-reductase inhibitor finasteride.
This study reported that prompt diagnosis and treatment with 5-alpha-reductase inhibitors and topical immunomodulators are key to mitigating the effects of frontal fibrosing alopecia and preventing permanent hair loss.
1 citations
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December 2012 in “Journal of dermatological science” This study introduces ficlatuzumab, an anti-HGF monoclonal antibody, in combination with gefitinib in a phase 2 trial to address EGFR TKI resistance in Asian NSCLC patients.
5 citations
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October 2019 in “JAAD Case Reports” This case report describes a young man with rapidly progressive cicatricial alopecia that shows features overlapping several other types, suggesting these conditions may exist on a spectrum.
January 1990 in “Medical Entomology and Zoology” This study developed a faster method for analyzing fatty acid ethyl esters in hair to help detect alcohol consumption levels, showing potential for applications in forensic and clinical settings.
5 citations
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February 2017 in “Australasian Journal of Dermatology” This report describes three cases of hair loss that appear consistent with cicatricial pattern hair loss, a possible new subtype of scarring alopecia presenting in a female pattern hair loss distribution.
20 citations
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January 2016 in “Intractable & Rare Diseases Research” In this clinical experience, treating frontal fibrosing alopecia with oral finasteride, hydroxychloroquine, tacrolimus, and excimer laser was associated with optimal results in patients with active inflammation.
26 citations
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October 2018 in “British Journal of Dermatology” This study found that high frequency use of sunscreen is associated with frontal fibrosing alopecia among women attending a specialist hair clinic in Australia.
September 2019 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” Isotretinoin at low doses effectively treats facial papules in frontal fibrosing alopecia.
5 citations
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September 2021 in “Journal of The American Academy of Dermatology” This study found a high prevalence of beard and eyebrow alopecia in male patients with frontal fibrosing alopecia, and suggests a potential link between hormonal imbalances and the condition.
6 citations
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October 2019 in “Case Reports in Dermatology” This report describes a case of fibrosing alopecia in a pattern distribution in a postmenopausal woman, highlighting its distinction from other forms of lichen planopilaris and pattern hair loss.
3 citations
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November 2020 in “Clinical, Cosmetic and Investigational Dermatology” This review summarizes the current treatment modalities for frontal fibrosing alopecia and provides a practical guide for clinicians, but reports no new clinical results.
54 citations
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November 2007 in “Actas Dermo-Sifiliográficas” Early diagnosis of frontal fibrosing alopecia is crucial to prevent permanent hair loss.
47 citations
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September 2013 in “Aaps Pharmscitech” This study found that liquid crystalline nanoparticles formulated with Cremophor surfactants significantly enhanced skin permeation of finasteride compared to lower surfactant concentrations.
March 2021 in “Arrow - TU Dublin (Technological University Dublin)” This study tested a folate-conjugate drug delivery system and found its cytotoxicity depends on whether the treated cells overexpress folate receptors, suggesting potential for targeted chemotherapy.
August 2021 in “Annals of Agricultural and Environmental Medicine” This review provides a detailed analysis of frontal fibrosing alopecia, focusing on its prevalence in postmenopausal Caucasian women, associated comorbidities, and potential autoimmune, genetic, hormonal, and environmental factors; it emphasizes the need for improved understanding to enhance diagnosis and treatment.
July 2018 in “Elsevier eBooks” This review discusses the evolving understanding of frontal fibrosing alopecia as a generalized skin condition with diverse manifestations, and reports no new clinical results.
January 2023 in “RSC Advances” This study found that two eco-friendly analytical methods for quantifying Finasteride and Tadalafil in a new dosage form were effective, green, and suitable for quality control.
October 2024 in “Journal of the Endocrine Society” This study examined uncharacterized CYP21A2 gene variants related to non-classic congenital adrenal hyperplasia and found that several mutations reduce enzyme activity, which may help improve diagnostic and treatment strategies.
June 2025 in “British Journal of Dermatology” This report describes two unusual cases of frontal fibrosing alopecia in men, highlighting potential vaccine-related immune triggers and genetic factors, especially regarding the pronounced facial papular phenotype observed.
September 2015 in “Dermatologic Surgery” In this study, the researchers developed a computer-aided imaging system to quantitatively measure baldness in Chinese women with female pattern hair loss, potentially improving the precision of severity evaluation compared to traditional scales.
March 2023 in “Journal of Cosmetic Dermatology” This case report illustrates that fibrosing alopecia in a pattern distribution may be misdiagnosed as androgenetic alopecia due to similar hair loss patterns, but distinctive trichoscopic and histopathologic features help differentiate it.
May 2025 in “Journal of Clinical Images and Medical Case Reports” The study observed that patterned fibrosing alopecia, a type of scarring hair loss, appears in some patients after hair transplants, facelifts, and other surgical interventions, sharing features with lichen planopilaris and androgenetic alopecia.
74 citations
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April 2017 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This study classified frontal fibrosing alopecia patients into three clinical patterns, finding that pattern III had the best prognosis and pattern II the worst after treatment with dutasteride and corticosteroids.
1 citations
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January 2020 in “Skin appendage disorders” Finasteride may help treat frontal fibrosing alopecia, but more research is needed.
8 citations
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August 2023 in “Lasers in Surgery and Medicine” This study observed that treating acne scars with fractional ablative laser concurrently with isotretinoin improved outcomes more effectively compared to applying the laser 6 months after isotretinoin treatment ended, as measured by the Quantitative Global Acne Scarring Grading System.
8 citations
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October 2019 in “International Journal of Dermatology” This study examined 56 Thai patients with frontal fibrosing alopecia, finding frontotemporal hairline recession and eyebrow loss were common, and reported better disease stabilization with combination treatments of topical corticosteroids with hydroxychloroquine or finasteride.
1 citations
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November 2020 in “Journal of The American Academy of Dermatology” The commentary suggests that certain hair and skin care products may be linked to frontal fibrosing alopecia, but not sunscreens, and calls for more thorough research on the causes.
11 citations
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May 2023 in “Journal of Cutaneous Medicine and Surgery” This study found that combining plasma rich in growth factors with conventional treatment significantly improved hair regrowth and reduced symptoms in patients with frontal fibrosing alopecia compared to conventional treatment alone.