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Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.

CRTH2 antagonists might be useful for treating many conditions because they play a role in immune and inflammation responses.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Low-Level Laser Therapy can stimulate healing and cell function, potentially leading to wider medical use.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

SOX9 is essential for the development of various organs and hair follicles.

Mice with enhanced regeneration abilities may help develop new regenerative medicine therapies.

Exosomes help nerve fibers grow by affecting specific cell signaling pathways.

Scientists made working salivary glands in mice using bioengineered cells, which could help treat dry mouth.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Researchers isolated a new type of stem cell from mouse skin that can renew itself and turn into multiple cell types.

Scientists made working hair follicles using stem cells, helping future hair loss treatments.

Lizards can regrow their tails, and studying this process helps understand scar-free healing and limb regeneration.

Fully regenerating human hair follicles not yet achieved.

Human skin's melanocytes respond to light by changing shape, producing pigments and hormones, which may affect sleep patterns.

Cell transplantation faces challenges in genitourinary reconstruction, but alternative tissue sources and microencapsulation show promise.

Targeted immunotherapy could be a promising new treatment for hair regrowth.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

New methods for skin and nerve regeneration can improve healing and feeling after burns.

Deleting the PTEN gene in mice causes nerve cells to grow larger and heal better after injury, but may cause overgrowth and hair loss in older mice.

Pica disorder in central Iraq is mainly found in females and is linked to low iron levels; treatment with iron improves most patients.

NF-κB is crucial for zebrafish heart repair, affecting heart cell growth and repair processes.

ePUKs could be valuable for regenerative medicine due to their wound healing abilities.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Skin abnormalities can indicate immunodeficiency due to shared origins with the immune system.

The paper suggests improving diagnosis and treatment of telogen effluvium but does not recommend a new classification system.

Epidermal stem cells could lead to new treatments for skin and hair disorders.