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This review examines the role of endothelial precursors and cellularized scaffolds in wound repair and revascularization for treating full thickness skin loss, but reports no new clinical results.

This study found that chitosan nanofibrillar scaffolds accelerated skin wound healing in mice by enhancing cell adhesion, proliferation, and regeneration of epidermis and dermis compared to other forms.

This review discusses the principles, materials, and applications of melt electrowriting-based 4D printing for creating biomimetic scaffolds, but reports no new clinical results; it highlights recent advancements and remaining challenges in the field.

This review updates on the development of liposomal carriers for delivering growth factors to improve tissue regeneration and highlights recent efforts to enhance their stability and retention in tissues.

This review explores recent advancements in skin tissue engineering using 3D bioprinting, discussing current methods, bioink formulations, and outlining both achievements and limitations without presenting new clinical results.

This review outlines strategies for regulating macrophage response using bioactive materials to enhance wound healing, focusing on extracellular matrix-based scaffolds and nanofibrous composites, but reports no new clinical results.

This study explores the transformative role of tissue engineering in cosmetics, highlighting innovations like lab-grown skin and personalized grafts that enhance product efficacy, offer ethical alternatives to animal testing, and address aesthetic issues such as scarring and aging.

This review introduces a framework to integrate bioinspired conductive materials and advanced 3D/4D printing in regenerative medicine for dynamic, responsive tissue regeneration, emphasizing the potential of smart scaffolds to adapt to physiological cues.

This review describes bioengineering strategies to mimic the natural cell microenvironment in vitro, emphasizing the novel approach of using cell-synthesized extracellular matrix as a scaffold for engineering functional 3D tissues, while highlighting the limitations of exogenous scaffolds in tissue engineering.

This article highlights the versatility and potential of alginate and its derivatives in tissue engineering applications, discussing their properties, modification techniques, and various uses in enhancing tissue healing, bone regeneration, and cell growth.

This review highlights the rapid advancements in 3D bioprinting techniques, emphasizing their role in enhancing regenerative therapy, drug delivery, and bioengineering applications while addressing current challenges in bioink formulation and bioprinting stability.

This review discusses how studying regenerative biology in certain mammalian models could enhance our understanding of complex tissue regeneration, but it reports no new clinical findings.

This study found that MDP hydrogel significantly accelerated wound healing and improved tissue formation in diabetic mice compared to a standard clinical hydrogel and control buffer.

Innovative methods are reducing animal testing and improving biomedical research.

This dissertation investigated barriers to clinical translation of adipose-derived mesenchymal stem cell-based vascular grafts, highlighting issues with thrombosis in diabetic patients and proposing alternative cell sources to improve applicability.

This study demonstrated that an engineered human skin equivalent can generate follicle-like structures resembling fetal skin, highlighting the role of the dermal compartment in directing epithelial cell fate in vitro.

This study found that using cultured mesenchymal stem cells from mouse whisker hair follicle outer root sheath in wound healing reduced inflammation, accelerated closure, and resulted in less hypertrophic scarring in mice.

This study found that engineered skin substitutes made with skin-derived precursors and epidermal stem cells can regenerate hair follicles after grafting into nude mice.

This review found that 3D bioprinting significantly advances skin tissue engineering by enabling the creation of complex, patient-specific skin structures, though technological and regulatory challenges persist, particularly in areas like scalability and physiological mimicry.

In this study, spiny mice showed superior cardiac recovery after myocardial infarction compared to other mouse strains, with enhanced myocardial preservation and functional stabilization.

This review evaluates the clinical use of composite dermal-epidermal skin substitutes, with a focus on advancements such as the "BioMask" for facial skin trauma, highlighting the potential of 3D bioprinting and bioengineered skin in improving wound treatment and reconstruction.

In this study, a pH-responsive microneedle patch was developed, showing potential in rat models for treating spinal cord injuries by reducing inflammation, promoting nerve regeneration, and supporting neurogenesis, which contributed to improved motor and neurological recovery.

This research presents a comprehensive workflow for producing EMA-compliant autologous keratinocyte-based therapies for wound healing and explores miRNA-mediated regulations in human keratinocytes and adipose-derived mesenchymal stem cells.

This study reported that treating wounds with a hydrogel from acellular porcine adipose tissue and adipose-derived stem cells may significantly enhance wound healing and regeneration by promoting new adipocyte formation.

This study observed that exosomes derived from adipose-derived stem cells significantly enhanced bone marrow mesenchymal stem cell migration and osteogenesis, leading to improved bone regeneration in a rat model of calvarial defects.

The authors concluded that burned skin contains viable mesenchymal stem cells which enhance wound healing in animal models without altering key biological functions due to burn trauma.

This review suggests that allogenic adipose stem cell and extracellular matrix transplants may be safe and effective for various medical conditions, based on available studies.

This review outlines the design and engineering of multifunctional hydrogels, emphasizing their evolving biomedical applications, notably in controlled drug delivery, tissue support, and disease management, and discusses their potential for clinical translation.

This review discusses the challenges of skin graft acceptance and examines current strategies and alternatives for full-thickness skin replacement and repair, noting that immunological rejection remains a significant hurdle.

This review examines the potential of mesenchymal stem/stromal cells in treating and possibly preventing allergic diseases, and reports no new clinical results.