Composite Skin Substitutes, 3D Skin Bioprinting, and the BioMask Concept in Regenerating Skin Defects - Review

The review discusses the challenges of treating skin trauma, particularly facial skin trauma, and explores alternatives to traditional autologous skin grafting, such as bioengineered skin substitutes. It highlights the potential of 3D skin bioprinting and the innovative "BioMask" concept for facial wound treatment. The review analyzes existing composite dermal-epidermal substitutes and materials in testing, emphasizing their role in effective pain reduction and skin injury reconstruction. The development of new technologies like "BioMask" is driven by the high demands of facial skin injury treatment, offering improved methods for wound dressing and skin defect reconstruction.