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    Glossary Cell-Mediated Immunity

    immune response involving T cells targeting infected or abnormal cells

    Cell-Mediated Immunity (CMI) is a type of immune response that does not involve antibodies but instead relies on the activation of certain immune cells, particularly T cells, to fight off pathogens, infected cells, and cancer cells. This form of immunity is crucial for defending against intracellular pathogens, such as viruses and some bacteria, and plays a significant role in transplant rejection and autoimmune diseases.

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    1. Performance of an interferon-γ release assay-based test for cell-mediated immunity to SARS-CoV-2 Frontiers in Immunology · 2023 · 3 citations
    2. Dermal T cell immunity and key regulatory signaling pathways: Implications in immune-mediated alopecia and hair regeneration Genes & Diseases · 2025 · 1 citations
    3. 0037 Inflammatory implications in female pattern hair loss: unraveling B cell-related immune activation through comparative transcriptome profiling Journal of Investigative Dermatology · 2025
    4. Alopecia Areata International Journal of Dermatology · 1985 · 14 citations
    5. Seasonal alopecia areata with atopy Journal of the American Academy of Dermatology · 1989 · 8 citations
    6. Grahams Little Piccardi Lausseur Syndrome - A Rare Case Report with Review of Literature International Journal of Science and Research (IJSR) · 2023
    7. 66-Year-Old Female with Itchy Scalp and Hair Loss Clinical Cases in Dermatology · 2022
    8. Case 7 Small Animal Dermatology · 2019
    9. Successful treatment of refractory alopecia universalis with infliximab: First case report in Sri Lanka The Sri Lanka Journal of Dermatology · 2017
    10. CAQ Corner: Basic concepts of transplant immunology Liver transplantation · 2022
    11. Evaluation of Serum Apelin-13 in Psoriasis Vulgaris Patients Benha Journal of Applied Sciences · 2020
    12. Down-RANKing the Threat of HSV-1: RANKL Upregulates MHC-Class-I-Restricted Anti-Viral Immunity in Herpes Simplex Virus Infection Journal of Investigative Dermatology · 2015 · 2 citations
    13. SIRT1 downregulation provokes immune-inflammatory responses in hair follicle outer root sheath cells and may contribute to development of alopecia areata Journal of Dermatological Science · 2023 · 13 citations
    14. Genome-wide association study in alopecia areata implicates both innate and adaptive immunity Nature · 2010 · 717 citations
    15. The role of B cell-activating factor system in autoimmune diseases: mechanisms, disease implications, and therapeutic advances Frontiers in Immunology · 2025 · 4 citations
    16. Exploiting Unique Features of Microneedles to Modulate Immunity Advanced Materials · 2023 · 39 citations
    17. Age-Related Loss of Innate Immune Antimicrobial Function of Dermal Fat Is Mediated by Transforming Growth Factor Beta Immunity · 2018 · 96 citations
    18. The vitamin B5/coenzyme A axis: A target for immunomodulation? European Journal of Immunology · 2024
    19. IMMUNOPATHOLOGY OF THE HUMAN HAIR FOLLICLE Dermatologic Clinics · 1999 · 15 citations
    20. In Human Skin, UVB Initiates Early Induction of IL-10 Over IL-12 Preferentially in the Expanding Dermal Monocytic/Macrophagic Population Journal of Investigative Dermatology · 1998 · 101 citations
    21. Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARα and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways Journal of Cellular Biochemistry · 2005 · 24 citations
    22. NFAT5 mediates hypertonic stress-induced atherosclerosis via activating NLRP3 inflammasome in endothelium Cell Communication and Signaling · 2019 · 50 citations
    23. Lymphocytic mediated alopecia: histological classification by pattern analysis Clinics in Dermatology · 2001 · 29 citations
    24. Gene Array Profiling and Immunomodulation Studies Define a Cell-Mediated Immune Response Underlying the Pathogenesis of Alopecia Areata in a Mouse Model and Humans Journal of Investigative Dermatology · 2002 · 114 citations
    25. Advances in Cell-Mediated Drug Delivery for Dermatologic Diseases: Mechanisms and Current Applications Pharmaceutics · 2025 · 2 citations
    26. DNMT1-mediated methylation inhibits microRNA-214-3p and promotes hair follicle stem cell differentiate into adipogenic lineages Stem cell research & therapy · 2020 · 8 citations
    27. Type 2 innate immunity regulates hair follicle homeostasis to control <i>Demodex</i> pathosymbionts bioRxiv (Cold Spring Harbor Laboratory) · 2021
    28. Mechanisms regulating skin immunity and inflammation Nature Reviews Immunology · 2014 · 610 citations
    29. Cell Membrane-Camouflaged Nanoparticles Mediated Nucleic Acids Delivery International Journal of Nanomedicine · 2023 · 10 citations
    30. Live imaging of skin immunity using two-photon microscopy: a short review Inflammation and Regeneration · 2026