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This review discusses how recent studies use models and experiments to understand immune system signaling, but it reports no new clinical findings; the authors suggest strategies for improving these models.

This review discusses various approaches to treating alopecia, including drug therapy and hair transplantation, but reports no new research findings; the authors highlight the need for novel techniques like cell culturing.

In this study, researchers found that Dicer, but not Tarbp2, plays a crucial role in regulating the growth phase of hair follicles in post-natal mice.

This study found that deleting ceramide synthase 4 in skin epidermis stem cells disrupts hair follicle and skin barrier function, leading to immune responses similar to atopic dermatitis, due to imbalances in lipid composition affecting differentiation.

This study used cashmere goats to map the differentiation of dermal papilla stem cells and identified key intermediate cell states involved in hair follicle regeneration.

This study found that early mitochondrial reprogramming, specifically through fatty acid oxidation fueling oxidative phosphorylation, is crucial for initiating differentiation in epidermal stem cells, highlighting a potential therapeutic target for differentiation defects in skin disorders.

This study found that selective inactivation of ribonucleotide excision repair in mouse epidermis led to spontaneous DNA damage, skin inflammation, and the development of squamous cell carcinoma, suggesting potential implications for cancer development in humans.

This study introduced a reproducible human model using 3D-SeboSkin technology to study hidradenitis suppurativa, allowing better maintenance of skin integrity and replication of biomarker expression patterns compared to traditional skin cultures, suggesting its value for further research.

This review examines how epigenetic dysregulation affects adult stem cell function, noting that impacts range from minor to serious disruptions in tissue homeostasis and potential cancer development.

This review highlights REV7's crucial roles in maintaining genome stability, its implication in several cancers, and its association with poor prognoses and treatment resistance, while also noting that REV7 suppression may improve chemotherapy sensitivity.

In this study, researchers found that CD4 is expressed on murine K5⁺ keratinocytes, and its expression is crucial for maintaining epidermal stem cell balance and wound repair capacity, particularly during aging.

This study found that extracellular vesicles from mesenchymal and outer root sheath stem cells may inhibit hair follicle stem cell apoptosis, suggesting potential therapeutic benefits for hair loss treatments.

This study found that Cyanidin-3-O-glucoside and Vitisin A were able to penetrate mouse skin and improve issues related to hair follicle miniaturization and apoptosis in androgenetic alopecia, suggesting these compounds as potential alternative treatments for hair loss.

This study found that PRC1 plays crucial roles in skin epithelial stem cell regulation, with catalytic and non-catalytic functions impacting epidermal integrity, hair development, and Merkel cell dynamics in murine models.

This study found that IGF1, retinoic acid, and dexamethasone increase IGFBP-3 production in cultured human dermal papilla cells, potentially inhibiting IGF1 action on hair growth.

This study identified key cells and pathways needed for the development of touch receptor patterns in mouse skin, notably that certain keratinocytes are crucial for innervation patterns, while Merkel cells and BMP signaling have distinct roles.

This study found that overexpression of the metabolic enzyme PHGDH can promote cancer initiation and progression, highlighting its significant role in tumor cell proliferation and tumorigenesis.

In this study, transgenic mice altered to express a Clim-inhibiting molecule under a keratin promoter showed corneal degradation and hair follicle failure, highlighting Clim proteins' role in maintaining these tissues.

This review summarizes recent insights into corneal limbal stem cell differentiation and the potential role of progenitor-like cells, but reports no new experimental results.

This review discusses the role of lamins in development, tissue maintenance, and stress response, and does not report new experimental findings.

This study found that, despite a major depletion of SOX2-expressing stem cells in the pituitary, there was no effect on endocrine cell homeostasis or response to certain stressors in adult mice.

In this study, CTCF was found to play essential roles in epidermal differentiation and skin barrier formation, simultaneously acting as a suppressor of epithelial inflammatory responses in mouse skin.

The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.

This study found that autophagy plays a novel role in human hair growth, with altered autophagic flux during hair development phases influencing hair follicle behavior in a preclinical model.

COL17A1 is crucial for preventing hair graying and loss by supporting hair and pigment stem cells.

This review examines the role of retinoic acid synthesis in hair follicles and sebaceous glands, focusing on its localization and function during normal and disease states, but reports no new results.

This study found that combining polybrene and a ROCK inhibitor can effectively expand human keratinocyte stem/progenitor cells carrying a transgene, aiding their use in regenerative medicine.

In this study, researchers found that cepharanthine significantly inhibited HSV-1 replication in vitro by interfering with specific signaling pathways, arresting the cell cycle, and inducing apoptosis in infected cells, highlighting its potential as an antiviral agent.

This review discusses stem cell behavior, highlighting their plasticity in tissue repair and the impact of somatic mutations on clonal expansion in early cancer, but reports no new experimental results.

This review discusses the role of signaling networks in sebaceous gland development and disorders, highlighting recent insights from mouse models and cell line studies, but reports no new experimental results.