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Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.

Ionizing radiation causes irreversible skin damage, with single doses leading to acute injury and hair graying, and fractional doses causing more severe long-term tissue damage.

Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.

Scarless healing is complex and influenced by genetics and environment, while better understanding could improve scar treatment.

Brg1 is crucial for keeping hair follicle stem cells and repairing skin, working with the Sonic Hedgehog pathway to promote hair growth.

Mathematical modeling can improve regenerative medicine by predicting biological processes and optimizing therapy development.

Stem cell self-renewal is complex and needs more research for full understanding.

Future research on ectodysplasin should explore its role in diseases, stem cells, and evolution, and continue developing treatments for genetic disorders like hypohidrotic ectodermal dysplasia.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

PBX1 reduces aging and cell death in stem cells by boosting SIRT1 and lowering PARP1.

Tofacitinib helped most patients with alopecia areata regrow hair and changes in immune cells were linked to the treatment's effectiveness.

Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

miR-140-5p in certain cell vesicles helps hair growth by boosting cell proliferation.

Green tea extract helps prevent cell death and supports cell survival in hair cells exposed to a chemotherapy drug.

Stem cell technologies and regenerative medicine, including platelet-rich plasma, show promise for hair restoration in treating hair loss, but more research is needed.

Nanotechnology could improve hair regrowth but faces challenges like complexity and safety concerns.

Improving the environment and cell interactions is key for creating human hair in the lab.

SOX9 is essential for the development of various organs and hair follicles.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

Different types of resting melanocyte stem cells have unique characteristics and vary in their potential to become other cells.

The PP2A-B55α protein is essential for brain and skin development in embryos.

The hair follicle is a great model for research to improve hair growth treatments.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.