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Arsenic exposure from contaminated water severely damages the skin, causing hair loss, pigmentation changes, irritation, and can lead to skin cancer.

New treatments for hair loss should target eight main causes and use specific plant compounds and peptides for better results.

The document concludes that drug repurposing, which is reusing known medicines for new illnesses, can provide faster, cheaper treatment options for various serious diseases, including cancer, COVID-19, and rare diseases.

Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.

Two unusual cases showed that Lichen Planopilaris can look like other skin conditions and need early treatment to protect hair.

Targeting TGFβ can improve skin immunity in older people.

Bendamustine combined with rituximab is an effective and well-tolerated treatment for certain types of lymphoma.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

Innate lymphoid cells help control skin bacteria by regulating sebaceous glands.

The Middle East and Africa need better data, treatment consensus, and support for Alopecia Areata.

Treg dysfunction is linked to various autoimmune skin diseases, and understanding Treg properties is key for new treatments.

Certain immune cells contribute to skin autoimmune diseases, and some treatments can reverse hair loss in these conditions.

Patients with Alopecia areata have fewer specific immune cells that normally regulate the immune system, which may contribute to the condition.

Estrogen increases a growth factor in hair cells which might affect hair loss.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Hamilton scale imprecise, hair shaft diameter decreases, stem cell transplant regrows hair, ECP ineffective for alopecia areata universalis.

FOXN1 gene variants cause low T cells and immune issues from birth.

CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.

Fetal skin has unique immune cells different from adult skin.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

Mast cells play a significant role in hair loss conditions like male pattern hair loss and alopecia areata.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

HDAC inhibitors, like Vorinostat and Entinostat, can help regrow hair in alopecia areata.

The document concludes that treatment for cutaneous T-cell lymphoma should be customized to each patient's disease stage, balancing benefits and side effects, with no cure but many patients living long lives.

T-cell reconstitution after thymus transplantation can cause hair whitening and loss.

New treatments targeting T-cell pathways are needed for better alopecia areata management.

Tissue environment greatly affects the unique epigenetic makeup of regulatory T cells, which could impact autoimmune disease treatment.

A new mutation in the TMEM173 gene and a risk allele in IFIH1 cause a unique set of immune-related symptoms.

Alopecia areata is an autoimmune condition causing hair loss, linked to genetic factors and immune system issues, with no cure yet.

Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.