Comparative Efficacy of Low-Dose Oral Minoxidil, Topical Minoxidil, and Platelet-Rich Plasma with Topical Minoxidil in Androgenetic Alopecia: A Randomized Controlled Trial

    June 2024 in “ British Journal of Dermatology ”
    P Janaani, Muthu Sendhil Kumaran, Keshavamurthy Vinay, Hitaishi Mehta, Vinod Sharma
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    TLDR Combining PRP with topical minoxidil is the most effective for increasing hair density in male pattern baldness.
    This randomized controlled trial compared the efficacy of low-dose oral minoxidil, topical minoxidil, and platelet-rich plasma (PRP) combined with topical minoxidil in treating androgenetic alopecia (AGA) in 66 male participants. Over 32 weeks, Group 3 (PRP with topical minoxidil) showed the most significant increase in terminal hair density, while Group 1 (oral minoxidil) was more effective in reducing vellus hair density. All treatments led to a reduction in hair diameter diversity and changes in Treg cell populations and signalling molecules, with no significant differences between the groups. The study supports low-dose oral minoxidil as a viable alternative to topical minoxidil and highlights the benefits of combining PRP with topical minoxidil.
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      community When are we getting a cure to hair loss?

      in Chat 1 year ago
      Potential treatments for hair loss, including Minoxidil, finasteride, RU58841 and various upcoming pharmaceuticals, gene editing and cloning. It is suggested that a cure, if found, would be highly profitable due to the large number of people affected by hair loss globally.

      community What else is good. Besides the big 3.

      in Chat  34 upvotes 2 months ago
      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

      community I just made my own PRP - DIY PRP

      in Research/Science  548 upvotes 1 year ago
      The post and conversation are about a user who made their own Platelet-Rich Plasma (PRP) for hair loss treatment at home, using their own blood and a centrifuge. The responses vary, with some users supporting the DIY approach to save money, others expressing concern about the safety and effectiveness of the method, and a few joking about the lengths people will go to combat hair loss.

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      in Chat  127 upvotes 1 year ago
      The conversation is about young men under 20 experiencing hair loss. They discuss their experiences and treatments used, including finasteride (fin) and minoxidil (min).

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