September 2022 in “Indian Journal of Paediatric Dermatology” This case report documents the first confirmed mutation-proved instance of Clouston syndrome in a large Chinese-Malaysian family, linked to the c.263C>T (A88V) mutation in the GJB6 gene, with no available treatment but highlighting the importance of genetic counseling.
November 2025 in “Indian Dermatology Online Journal” This case report describes a patient with Clouston syndrome who developed squamous cell carcinoma, highlighting the need for regular follow-up in patients with chronic paronychia that do not respond to conventional treatments.
March 2021 in “Annals of King Edward Medical University” This report details a case of a 3-year-old child with Clouston syndrome, a rare inherited disorder affecting nails, skin, and hair, highlighting the need for supportive management due to the absence of treatment options.
November 2025 in “Biomedicines” This review highlights hypochlorous acid's potential benefits in various medical fields due to its antimicrobial and healing properties but stresses the need for further research on dosing and product development.
3 citations
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May 2021 in “Genetics and Biodiversity Journal” In this study, the ethanolic extract of Citrullus colocynthis demonstrated strong antioxidant activity and reduced cancer cell numbers in vitro, suggesting potential for pharmacological use.
January 2025 in “Clinical Cosmetic and Investigational Dermatology” This case series involving 10 patients treated with clascoterone cream 1% for acne vulgaris found it effective and well-tolerated, regardless of severity, age, gender, or ethnicity, and noted additional benefits for related skin conditions.
September 2025 in “Journal of International Medical Research” In this case study, researchers documented chronic dermatitis and ulcerative lesions in a 70-year-old Syrian man following chlorine gas exposure during the conflict, highlighting the need for healthcare planning and registries to manage long-term effects in affected populations.
86 citations
,
August 2011 in “Toxicological sciences” In this study, researchers found that TCDD exposure accelerated differentiation and altered gene expression in human epidermal cells, indicating the epidermal barrier as a target of TCDD-activated AHR.
November 2025 in “Journal of Investigative Dermatology” PCFCL may have unrecognized subtypes and needs more research.
5 citations
,
May 2020 in “Clinical and Experimental Dermatology” This correspondence discusses clascoterone as a potential new treatment for androgenetic alopecia but reports no clinical results.
29 citations
,
October 2020 in “Environmental health perspectives” This study found that several preservatives, including triclocarban and triclosan, showed potential endocrine-disrupting effects on various nuclear receptors in both in silico and in vitro models.
January 2007 in “Leather Science and Engineering”
9 citations
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April 2021 in “Expert opinion on pharmacotherapy” This review highlights that clascoterone, a newly FDA-approved topical androgen antagonist, effectively reduces both non-inflammatory and inflammatory acne lesions with no systemic effects, making it a promising new option for acne treatment in both male and female patients.
1036 citations
,
August 2019 in “Cells” This article provides an overview of mesenchymal stem cells, highlighting their extraction methods, differentiation potential, and applications in regenerative medicine, but reports no new clinical findings.
489 citations
,
November 2021 in “Signal Transduction and Targeted Therapy” This review discusses the composition, activation, and regulation of the JAK/STAT pathway and highlights its role and inhibitors in various diseases, but reports no new experimental results.
426 citations
,
August 2014 in “Nature Medicine” This narrative review examines the interactions between skin stem cells and their niches, finding new insights from advancements in genetic and imaging tools but reporting no new experimental results.
365 citations
,
November 2018 in “Journal of Allergy and Clinical Immunology” This review discusses the role of the skin microbiome in maintaining health and modulating atopic dermatitis, emphasizing the need for novel therapeutic strategies, but reports no new clinical results.
353 citations
,
November 2014 in “Molecular immunology” This review discusses the immune functions of porcine skin and proposes a classification of dendritic cell subsets based on similarities to human skin, but it reports no new clinical results.
346 citations
,
April 2020 in “Frontiers in Oncology” This review discusses the roles of key epithelial-mesenchymal transition factors and potential therapeutic opportunities involving cancer metabolic pathways, reporting no new clinical results.
249 citations
,
November 2018 in “Cell” TNFα helps grow and maintain liver cells in 3D culture for a long time.
248 citations
,
August 2015 in “Pharmacological Research” This review discusses case reports of autoimmune diseases following vaccination and the challenges of establishing a clear epidemiological connection, urging further investigation into vaccine-induced autoimmunity.
245 citations
,
April 2009 in “Circulation Research” This study found that human fetal CD133+ progenitor cells and their conditioned medium accelerated wound healing and promoted angiogenesis in a mouse model of ischemic diabetic ulcers through paracrine mechanisms involving Wnt signaling.
228 citations
,
June 2021 in “Frontiers in Immunology” This review discusses the role of macrophages in chronic wound healing and suggests that understanding their regulation can inform therapeutic approaches, but it reports no new results.
181 citations
,
January 2019 in “Cell” In this research, authors found that skin-resident ILCs regulate sebaceous gland function and microbial balance, emphasizing an immune-epithelia system that supports host-microbe symbiosis.
142 citations
,
March 2019 in “Molecules/Molecules online/Molecules annual” This review discusses the role of the endocannabinoid system in skin health and disease, highlighting its potential for future research and applications, but reports no new experimental results.
130 citations
,
March 2014 in “Proceedings of the National Academy of Sciences of the United States of America” This study found that in mice, epidermal Wnt/β-catenin signaling influences adipocyte differentiation and hair growth, suggesting its critical role in synchronizing adipogenesis with the hair growth cycle.
124 citations
,
November 2019 in “International Journal of Molecular Sciences” This review discusses different processing methods for isolating human AD-SVFs/AD-MSCs using various kits and reports no new clinical results, highlighting the need for standardized preparation techniques.
118 citations
,
April 2020 in “Stem Cell Research & Therapy” This study found that adipose-derived mesenchymal stromal cell secretome, particularly when preconditioned with IFNγ, significantly influences cell motility and anti-inflammatory responses, enhancing its potential as a regenerative therapy.
116 citations
,
April 2020 in “Stem Cell Research & Therapy” This study identified highly variable genes in mesenchymal stem/stromal cells that are linked to classic functions like development and inflammation response, suggesting their potential as markers for further potency studies.
107 citations
,
October 2022 in “Frontiers in Immunology” This bibliometric analysis examines the research landscape of T cells in atherosclerosis and identifies key trends and emerging research areas, highlighting the field's stabilization over the past decade.