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Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

Eating well and avoiding synthetic hair products are key for healthy hair.

Platelet-rich plasma therapy may have benefits and is generally safe, but more research is needed to confirm its effectiveness and safety.

Birth control pills slightly increase the risk of breast cancer, especially if used before the first full-term pregnancy.

Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.

Minoxidil showed a 30% success rate for hair growth in a study, and various skin treatments were effective, but some had limitations or side effects.

The vitamin D receptor can act without its usual activating molecule, affecting hair growth and skin cancer, but its full range of actions is not well understood.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

Biodegradable polymers can improve cannabinoid delivery but need more clinical trials.

Lifestyle choices like stress, smoking, heavy drinking, sun exposure, and chemical hair treatments might speed up hair loss in people with androgenetic alopecia.

TCDD disrupts skin stem cells, causing skin issues like chloracne.

Exosomes could be a promising way to help repair skin and treat skin disorders.

Inhibiting ODC can prevent UV-induced skin cancer.

Natural volatiles and essential oils have health benefits and can enhance the effects of some medicines, but more research is needed to understand how they work and their possible side effects.

The new patch for treating mouth sores releases medicine slowly, sticks well, and helps healing without the side effects of current creams.

Prostaglandins and the enzyme AKR1C3 could play a role in skin cancer and hair loss, and further research is needed to understand these mechanisms.

The research showed how melanocytes develop, move, and respond to UV light, and their stem cells' role in hair color and skin cancer risk.

Autophagy helps control skin inflammation and cancer responses and regulates hair growth by affecting stem cell activity.

Two patients treated with TAC for mouth fibrosis improved but developed Cushing's Syndrome symptoms.

Hair follicle stem cells can form both hair follicles and skin.

Vitamin D is important for bones, hair, blood pressure, and breast development.

The fish oil-based gel with imiquimod improves skin cancer treatment and reduces inflammation.

Vitamin D is important for skin health and can help treat psoriasis, atopic dermatitis, and vitiligo.

The document concludes that Hidradenitis suppurativa is often underdiagnosed, lacks definitive treatment, and requires better awareness and management strategies.

Stopping mitochondrial respiration can prevent brain cancer spread in skin cancer patients, and plant compound β-sitosterol could help achieve this.

PTEN helps control the number and health of skin stem cells by working with the protein BMAL1.

Innate immunity genes in hair follicle stem cells might have new roles beyond traditional immune functions.

The Bcl-2 protein is important for keeping hair follicle stem cells working and preventing hair loss.

Blocking certain immune signals can reduce skin damage from radiation therapy.

Unconventional lymphocytes are important for quick immune responses and healing of skin and mucosal barriers.