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Mutations at Val-889 and Arg-752 disrupt key interactions in the androgen receptor, affecting its function.

Agouti protein affects melanocortin receptors through competitive antagonism and receptor down-regulation.

Manatee whiskers are specially adapted for touch in water.

FLRG and follistatin have different roles in wound healing.

Noggin is necessary to start the hair growth phase in skin after birth.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

A cluster of sulfur-rich hair protein genes was found on chromosome 17.

The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Four-amino acid part makes enzyme sensitive to finasteride.

The 190-kbp domain contains all human type I hair keratin genes, showing their organization and evolution.

The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

The new skin patch with human matrix and antibiotic improves wound healing.

Hair growth is controlled by specific gene clusters and proteins, and cysteine affects hair gene expression in sheep.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

New research on prostamide F2α has led to treatments for glaucoma and eyelash growth and may have more medical uses.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Vitamin D3 can help improve hair growth by enhancing the function of specific skin cells and could be useful in hair regeneration treatments.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Hairless protein is crucial for healthy skin and hair, and its malfunction can cause hair loss.

Sp6 promotes tooth development by reducing follistatin levels.

The study found that variations in hair protein genes are likely due to evolutionary deletions or duplications.

Mutations in certain receptors can cause diseases and offer new treatment options.