January 2023 in “Sovremennye problemy nauki i obrazovaniâ” Miliacin may help prevent hair loss and improve hair growth in mice with a condition similar to human baldness.
December 2020 in “Jurnal Kedokteran Hewan” In this study, researchers found that cayenne leaf extract significantly enhanced hair length and quantity in mice, with a 10% concentration being the most effective for stimulating growth.
November 2025 in “Advanced Science” In this study, researchers found that a cold atmospheric plasma-activated hydrogel containing interleukin-2 significantly enhanced hair regeneration in a depilated mouse model, promoting larger hair follicles and faster hair growth phase transition, suggesting it as a potential treatment for hair loss.
February 2023 in “Reactions Weekly”
2 citations
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January 2014 in “The Korea Journal of Herbology” This study found that Polygoni Multiflori Radix (PMR) reduced collagenase and elastase activity after UVB damage in fibroblasts, suggesting potential anti-aging properties for cosmetic use.
8 citations
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November 2010 in “British journal of dermatology/British journal of dermatology, Supplement” This study found that calcitriol protects keratinocytes from the cell detachment and apoptosis caused by captopril exposure.
April 2024 in “JURNAL ILMU KEFARMASIAN INDONESIA” This study examined how varying concentrations of kaolin base in mud masks with red pomegranate peel extract influenced properties like viscosity, pH, and drying time, finding that a formulation with 22.5% kaolin performed best in terms of physical characteristics and enzyme inhibition.
7 citations
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April 2021 in “Journal of advanced pharmaceutical technology & research” This study reported that compound 16 (olean-12-en-3beta-ol, cinnamate) from Merremia peltata showed potential as an androgen receptor antagonist, suggesting it may benefit alopecia treatment based on molecular docking and ADME-Tox predictions.
January 2026 in “Magazine Portal Bibliotech Digital (Universidad Nacional de Colombia)” This study found that rosemary extracts, both individually and in combination as shampoo and hair tonic, stimulated significant hair growth in male C57BL6//BIOU mice, even surpassing the growth achieved with the commercial drug 5% minoxidil.
January 2009 in “China Practical Medicine” This study found that several genes, including capping protein, palladin, VEGF, and HSPC-related clones, might cooperatively influence the aggregation, proliferation, and cycle control of dermal papilla cells, potentially affecting hair follicle behavior.
3 citations
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November 2022 in “Frontiers in molecular biosciences” This study suggests that in mice, plasmalogens may enhance hair growth by activating TRPC4 channels, which increases calcium influx and subsequently stimulates AMPK in hair follicles.
February 2023 in “Frontiers in Pharmacology” This study found that the water extract of Cacumen Platycladi promotes hair growth and follicle development in mice, possibly by influencing dermal papilla cells through the Akt/GSK3β/β-Catenin signaling pathway.
15 citations
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June 2021 in “International Journal of Molecular Sciences” This study demonstrated that novel curcumin analogs CMC2.24, CMC2.23, and CMC2.5 were more effective and less toxic than parent curcumin in inhibiting melanin production in normally pigmented human melanocytes, suggesting potential for skin depigmentation therapies.
12 citations
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November 2020 in “Molecules” This study found that carvone, a plant-derived compound, decreases melanin content and inhibits melanoma cell proliferation through the cAMP pathway, suggesting potential benefits for treating melanomas and other hyperpigmentation disorders.
10 citations
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September 2013 in “Veterinary dermatology” This study found that medroxyprogesterone injections led to partial or complete hair regrowth in some Pomeranian dogs with alopecia X, though their IGF-1 levels remained unchanged.
3 citations
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August 2013 in “Stem cells” This study found that topical application of partial proteasomal inhibitors accelerates hair growth by stabilizing β-catenin and disrupting the hair cycle's normal balance of activation and quiescence.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated Korean herbal compounds in silico and identified Biochanin A, Saponin Re, and Emodin as potential topical treatments for androgenetic alopecia, each with specific safety and efficacy considerations.
May 2024 in “EAS Journal of Pharmacy and Pharmacology” In this study, researchers used molecular docking to show that compounds from pomegranate peels, such as apigenin, luteolin, and taxifolin, effectively inhibit the enzyme 5α-reductase, suggesting potential anti-alopecic properties.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that the PPARγ modulator NAC-GED-0507-Levo may protect hair follicles from chemotherapy-induced damage, potentially offering a strategy to address irreversible hair loss in cancer patients.
January 2026 in “Saudi Journal of Medical and Pharmaceutical Sciences” In this study, researchers developed mango pectin-based hair gels for traction alopecia in black women, finding the gels exhibited beneficial properties for hair and good stability, suggesting potential as phytocosmetic treatments without common adverse effects.
August 2023 in “Journal of controlled release” This research found that STAR particles, ceramic particles with microneedles, significantly enhance skin permeability and improve the topical delivery of drugs like minoxidil and acyclovir, effectively promoting or inhibiting hair growth without causing skin irritation in ex vivo pig skin and rat models.
May 2001 in “Hair transplant forum international” This article discusses the use of a high-magnification digital video microscope for diagnosing and treating androgenetic alopecia and reports no new clinical results.
6 citations
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May 2020 in “Pharmacology Research & Perspectives” This study in rats found that a new hydroxypropyl-β-cyclodextrin formulation of minoxidil reduced the adverse cardiovascular and proliferative effects seen with traditional minoxidil solutions.
July 2021 in “Belarusian State Pedagogical University repository (Belarusian State Pedagogical University)” In this study, PMC was identified as a promising plant for nourishing hair, with effective hair growth promotion and 5α-reductase inhibition observed in both laboratory and animal studies for androgenetic alopecia treatment.
4 citations
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January 2021 in “in Vivo” This study found that scoparone increased the expression of certain pluripotency-related proteins in dermal papilla cells, suggesting a potential new mechanism for enhancing hair growth.
3 citations
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July 2020 in “International Journal of Applied Pharmaceutics” This study evaluated shampoo formulations containing banana corm extract and found that they possess favorable physical and stability characteristics, suggesting potential as a natural haircare product.
August 2026 in “International Journal of Molecular Sciences” This study found that Atractylodes macrocephala Koidz. extract promotes anagen entry and hair regrowth by enhancing dermal papilla cell activity and supporting hair cycle progression in a mouse model.
13 citations
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January 2010 in “Immunopharmacology and immunotoxicology” This study found that increased Bcl-2 protein expression after DPCP treatment was associated with hair regrowth in alopecia areata patients, suggesting its role in inhibiting apoptosis.
April 2024 in “Journal of Cytology” In this case study, researchers describe a rare instance of pilomatricoma with ossification in a 32-year-old woman, highlighting specific histopathological features and the role of bone morphogenic proteins and macrophages in its development.
December 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” In this study, researchers created a coamorphous system combining tadalafil and finasteride that demonstrated improved solubility, dissolution, and stability compared to their physical mixture, offering potential therapeutic advantages for benign prostatic hyperplasia.