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Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.

The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.

A team approach is crucial for managing PCOS, with dermatologists playing a key role.

Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.

Minoxidil helps prevent stress-caused hair loss in mice.

The document concludes that freeze-dried platelet-rich plasma shows promise for medical use but requires standardization and further research.

The 3D scaffold helped maintain hair cell traits and could improve hair loss treatments.

Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

Alopecia areata is an autoimmune hair loss condition treated with corticosteroids, and histologic confirmation is the best diagnosis method.

The document concludes that menopause should be seen as a natural part of aging and managed with personalized care and informed choices.

Finasteride doesn't affect bone density in male rats.

COVID-19 may cause early hair loss similar to classic temporary hair loss, with further research needed.

Certain fats in the skin help control inflammation and health, and changing these fats through diet or supplements might treat skin inflammation.

Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.

Allergic reactions to blood thinners are rare but can be serious, requiring careful management and alternative treatments.

Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.

Certain microRNAs are linked to various skin diseases and could be used to diagnose and treat these conditions.

Hair loss involves immune responses, inflammation, and disrupted signaling pathways.

Safflower has been used in traditional medicine for centuries and shows promise in treating heart, brain, and inflammatory conditions, but more research is needed to ensure its safety.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

Cheonggukjang may help prevent and manage various diseases and improve overall health, but its odor and safety concerns need addressing.

Antidepressants might help with skin inflammation and improve conditions like psoriasis and eczema.

Topical vitamin D is useful for some skin conditions but not effective for others, and more research is needed.

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

A cream with a specific hormone blocker increases hair growth in mice.

Taking spironolactone and linestrenol for androgen excess can lead to lower bone density in young women.