Anthralin (Dithranol) in Dermatology

September 2014 in “ International Journal of Dermatology ”

Virendra Sehgal, Prashant Verma, Ananta Khurana

anthralin dithranol alopecia areata keratinocyte proliferation anti-inflammatory effects short contact therapy UVB irradiation scalp psoriasis nail psoriasis childhood psoriasis minoxidil Ingram regimen anthralin minute entire skin treatment Rogaine

From the encyclopedia

Alopecia Areata →

autoimmune disorder causing patchy hair loss

Minoxidil →

An essential vasodilator with some anti-androgenic effects

Studysummary This article reviews anthralin's pharmacology, mode of action, and its use for psoriasis and other dermatoses, but reports no new clinical results.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

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Research cited in this study

6 / 6 results

research Bilateral Treatment for Alopecia Areata

9 citations , July 2010 in “Pediatric dermatology”

In this case study, a 4-year-old girl with alopecia areata showed hair regrowth only on the side treated with corticosteroids, not the side treated with anthralin.

research Alopecia Areata: Overview and Treatment Options

151 citations , February 2007 in “International Journal of Dermatology”

This review explores the causes and mechanisms of alopecia areata and discusses current treatments, reporting no new clinical findings.

research Old Wine in New Bottles: Reviving Old Therapies for Alopecia Areata Using Rodent Models

17 citations , September 2003 in “Journal of Investigative Dermatology Symposium Proceedings”

This study found that anthralin and mechlorethamine were the most effective therapies among those tested in AA-affected rodent models, providing a basis for further analysis of their mechanisms in Alopecia Areata.

research The Treatment of Alopecia Areata

17 citations , December 2001 in “Dermatologic therapy”

This review discusses various treatment options for alopecia areata tailored by age and severity, providing a practical algorithm, but reports no new clinical results.

research Treatment-Resistant Alopecia Areata: Combination Therapy with Minoxidil and Anthralin

46 citations , June 1990 in “Archives of dermatology”

In this study, combination therapy with 5% minoxidil and 0.5% anthralin showed some cosmetic improvement in 11% of patients with severe treatment-resistant alopecia areata, with hair regrowth starting by week 12.

research Evaluation of Anthralin in the Treatment of Alopecia Areata

109 citations , November 1987 in “Archives of dermatology”

In this study, 0.5%-1.0% anthralin cream led to a cosmetic response in 25% of patients with severe alopecia areata, despite common side effects like pruritus and erythema.