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      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

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      a JAK inhibitor for alopecia areata and other autoimmune conditions

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      community Does finasteride/dutasteride reverse aging?

      in Chat  45 upvotes 5 months ago
      Finasteride and dutasteride can improve skin texture and reduce acne by lowering DHT but do not reverse aging. They may enhance skin and hair health for some, but can also cause side effects like dry skin and sexual dysfunction.

      community 5-Months Update: Minoxidil + Red Light Therapy + Lifestyle Changes

      in Progress Pictures  1011 upvotes 1 month ago
      The user reported positive hair regrowth after 5 months using Minoxidil, red light therapy, and lifestyle changes, including dietary improvements and stress reduction. They chose natural supplements like saw palmetto and beta-sitosterol over pharmaceutical DHT inhibitors like finasteride.

      community Rejected for the 2nd time for the VDPHL01 Clinical Trials (believe it or not!)

      in Chat  12 upvotes 1 week ago
      The user was rejected from participating in a clinical trial for an extended-release oral Minoxidil due to having rheumatoid arthritis, despite initially being accepted. They had stopped using Dutasteride and Minoxidil to qualify but continued using other treatments like RU58841 and red light therapy.

      community 21 months on topical minoxidil and full HRT

      in Transgender  214 upvotes 11 months ago
      The conversation is about a transgender individual's experience with hair regrowth using topical minoxidil and hormone replacement therapy (HRT), expressing concern about the slow growth and thin appearance of their hair. Some responses encourage patience and highlight the variability of results, while others discuss the role of HRT and its effects.