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This study reports the crystal structure and geometric parameters of a modified Finasteride derivative, highlighting significant differences in dihedral angles compared to its solvated analog and computational models.

This study by Moore et al. (2025) provides the first evidence linking C-tactile afferents in humans to hair follicles, showing that these nerve fibers respond to hair movement rather than skin deformation, adding complexity to the understanding of their role in emotion and touch.

This study provides insight into the specific disulfide bond interactions between keratins and keratin associated proteins, suggesting non-random cysteine interactions crucial for stabilizing hair fiber structure.

This study found that excessive heat caused the most significant structural changes in hair from Caucasian and Afro samples, especially when combined with other treatments like bleaching and straightening.

This study found that the Pseudomonas sp. T5-6-I strain significantly increased selenium accumulation and root hair density in Brassica oleracea, highlighting its potential for phytoremediation and biofortification.

In this study, researchers identified a three-step process underlying age-related curved hair from cyclical extension: surface lipid transfer, specific disulfide bond cleavage, and unraveling of α-helices into β-structures, which may inform care strategies to manage hair curvature.

A new compound was made that might help treat diseases related to male hormones.

This study determined the crystal structure and conformation of synthesized 17x-Acetoxy-pregn-4,6-diene-3,20-dione, revealing specific molecular interactions and structural details in an orthorhombic crystal system.

In this study, PEG and keratin scaffolds selectively influenced protein release rates based on charge and size, suggesting their potential for targeted delivery of protein therapeutics.

A new antiandrogen compound was made and its detailed three-dimensional shape was described.

This review summarizes the roles of PDGF and its receptors in cell development and wound healing, reporting no new research findings; the authors emphasize PDGF's diverse biological functions.

This study found that Caesalpinia bonduc seed extracts significantly reduced prostate weight and improved prostate tissue morphology in Wistar rats with testosterone-induced benign prostatic hyperplasia.

This study developed a metal-free method for synthesizing sulfinimidate esters, showcasing their potential as versatile intermediates for enantioselective bond formation under mild conditions.

This study describes Hg(OTf)2 as a new and efficient catalyst for various organic synthesis reactions, including alkyne hydration and C–C bond forming cyclizations.

The new compounds may be more effective and cheaper than current treatments for conditions like baldness.

This study suggests that specific structural features of minoxidil analogs, such as hydrophobic and hydrogen bond field contributions, are key to enhancing lysyl hydroxylase inhibitory activity, which could inform future hair growth treatments.

In this study, researchers found that ligand homodimerization controls the receptor binding specificity of the FGF9 subfamily, preventing off-target activation of FGFR "b" isoforms.

This study found that 1,4-n-butylene dimaleate can restore the mechanical properties of reduced hair by reconnecting disulfide bonds and improving the hair's structural integrity using a thiol-Michael click reaction, compared to untreated reduced hair.

This study characterized the crystal structures and supramolecular architectures of new salts made from 2,4-diaminopyrimidine and different dicarboxylic acids, revealing subtle differences in crystal packing and hydrogen-bonding patterns, particularly influenced by sulfur atom interactions, through Hirshfeld analysis and enrichment ratios.

This study describes the molecular conformation and intermolecular interactions in the crystalline structure of the compound C24H31BrO4.

This study reported that while no synthesized compounds surpassed finasteride in 5α-reductase inhibitory activity, certain 4-azasteroid-2-oximes exhibited notable inhibition.

This research quantified the fidelity of human mitochondrial DNA polymerase and found it averages 1 error in 440,000 nucleotides, impacting its function related to disease and mitochondrial health.

A new compound that could treat various androgen-related conditions was created and analyzed.

The document concludes that a compound with potential for treating prostate cancer and hair loss was successfully made and its detailed structure was confirmed.

This study found that octahydrobenzo[c]quinolizin-3-one derivatives, particularly compound 3, were potent and selective inhibitors of the enzyme 5α-reductase type 1.

This study found that a synthetic avicequinone C analogue, 5e, was significantly more potent in inhibiting steroid 5α-reductase type 1 activity in human keratinocytes compared to the original isolated compound.

This study found that Avicennia marina extract and its active compound avicequinone C inhibit enzymes and receptors related to androgenic alopecia, potentially supporting hair growth in cultured dermal papilla cells.

This review provides an in-depth analysis of the structure and function of c-kit activation, and its role in both normal physiological and pathological conditions, with no new research findings reported.

This study found that compound 10 inhibited testosterone conversion to DHT in hamster flank organs and seminal vesicles, whereas compound 11's inhibitory effect varied with dose, linked to halogen electronegativity differences.

This study found that the methanolic heartwood extract of Avicennia marina significantly inhibits 5α-reductase type 1, reducing 5α-DHT production by 52% in a cell-based assay with human hair dermal papilla cells.