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Small proline-rich proteins and trichohyalin help make epithelial tissues tougher and more flexible.

Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.

Certain genetic markers, especially the MICA gene, are linked to alopecia areata.

A specific RNA, circNlgn, contributes to heart damage and scarring caused by the cancer drug doxorubicin.

Epidermolytic ichthyosis can be inherited in a semidominant way with mild symptoms in carriers.

Lipases, especially gehB, are crucial for Staphylococcus aureus to enter and colonize hair follicles.

Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.

Understanding keratinization is crucial for treating skin conditions like ichthyoses and psoriasis.

Wounded skin cells can revert to stem cells and help heal.

Only a few hair-specific keratins are linked to inherited hair disorders.

Edar signaling is crucial for controlling hair growth and regression.

Clim proteins are essential for maintaining healthy corneas and hair follicles.

The enzyme DHHC13 is essential for healthy hair and skin, and its deficiency leads to hair loss and skin problems.

Cells with active Wnt signaling are less likely to turn into cancer when exposed to a cancer-causing gene.

Blocking YAP/TAZ could be a new way to treat skin cancer.

New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.

Blocking specific proteins can help remove aging cells and might treat age-related diseases and promote hair growth.

OsPHR2 gene causes excessive phosphate in rice shoots, affecting plant growth and root development.

YAP and TAZ are crucial for skin cell growth and repair.

Reactive oxygen species (ROS) help control plant growth and development.

Metabolic signals and cell shape influence how cells develop and change.

Understanding wool keratin-associated proteins in sheep can help improve wool quality through selective breeding.

Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.

PRC2 is essential for maintaining intestinal cell balance and aiding regeneration after damage.

FGF5 gene mutations cause long hair in domestic cats.

Protein microarrays are highly sensitive tools useful for disease diagnosis and studying proteins.

Three genes in Arabidopsis are important for plant growth and development by affecting sugar attachment to proteins.

Trichohyalin-like proteins are essential for the development of skin structures like hair, nails, and feathers.

HOXC13 is essential for hair and nail development by regulating Foxn1.

The protein FLCN is involved in cellular cleanup and is regulated by ULK1.