Search

everythinglearnresearchcommunity

for

Search:↓

Decreased CD200 in hair follicles may cause immune issues in some alopecia areata cases.

Minoxidil increased small openings in blood vessel walls near growing hair in rats.

Certain immune cells contribute to severe hair loss in chronic alopecia areata, with Th17 cells possibly having a bigger impact than cytotoxic T cells.

Scientists have made progress in understanding hair follicle stem cells, identifying specific genes and markers, and suggesting their use in treating hair and skin conditions.

Low fluence photoepilation temporarily removes hair by targeting the hair follicle's pigmented area without severe damage.

Damaged hair follicle stem cells can cause permanent hair loss, but understanding their role could lead to new treatments.

Type 1 diabetes often occurs with other autoimmune diseases, and personalized treatment based on genetics can improve outcomes.

Alopecia areata shows a unique type 1 interferon signature, suggesting potential treatment by targeting this pathway.

Flightless I protein affects hair growth, with low levels delaying it and high levels increasing hair length in rodents.

Transplanted transected hair follicles can survive but grow at unsatisfactory rates and are thinner, suggesting limited potential for unlimited donor hair supply.

Cutting hair follicles into pieces for transplantation results in poor growth and thinner hair, and the technique is more invasive than previously thought.

Human skin cells contain Protease Nexin-1, and male hormones can decrease its levels, potentially affecting hair growth.

CD90 is present on specific cells in dog hair follicles.

A KRT71 mutation in Hereford cattle in Uruguay causes thin, curly hair and scaly skin.

A woman with alopecia totalis regrew dark hair in bands after using a corticosteroid ointment.

K6hf is a unique protein found only in a specific layer of hair follicles.

Current and future treatments for alopecia areata focus on immunosuppression, immunomodulation, and protecting hair follicles.

Claudin-1 is important for the barrier function and growth of hair.

The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.

Steven Kossard classified lymphocyte-related hair loss into four patterns, each linked to different types of baldness.

The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.

Skin stem cells can help improve skin repair and regeneration.

Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.

Hair and nail cells share similar proteins, indicating a common differentiation pathway.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

Different types of hair loss in lupus need careful diagnosis for proper treatment.

Type I interferons play a key role in the development of various skin diseases.