January 2013 in “China Animal Husbandry & Veterinary Medicine” This study established an optimal in vitro culture system for fine-wool sheep hair follicle stem cells, finding a combination of two-step enzymatic digestion and mechanical separation to be the most effective method.
17 citations
,
May 2005 in “Hair transplant forum international” This study evaluated the effectiveness of follicular units and growth factors derived from autologous platelet-rich plasma in improving hair growth and density in 23 male patients with pattern hair loss.
18 citations
,
July 2007 in “Hair transplant forum international” This study reported that using platelet-rich plasma as a storage medium for hair grafts in hair restoration surgery may improve graft survival rates and accelerate healing.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, Mononuclear Cells provided site-specific protection against chemotherapy-induced alopecia in rats treated with Ara-C, but not with CTX or VP-16, while PRP showed no protective effect.
This study suggests that platelet-rich plasma may provide short-term improvement in hair density for female pattern hair loss, but results varied and more rigorous trials are needed to establish optimal protocols.
September 2022 in “World Journal of Advanced Research and Reviews” This study introduced a Density-Calibrated Airtouch Protocol (DCAP) that suggests customizing the Airtouch hair coloring technique based on client hair density to optimize color blend, pigment longevity, and hair health.
1 citations
,
October 2025 in “Frontiers in Bioengineering and Biotechnology” This study developed a multifunctional bilayer dressing containing nanosilver and basic fibroblast growth factor, which improved wound healing by preventing bacterial penetration, promoting angiogenesis and hemostasis, and accelerating cell proliferation and migration, outperforming a control group by increasing healing rates by 47% in vivo.
January 2010 in “Journal of Animal Science” This study demonstrated that transcutaneous vaccination via cyanoacrylate skin surface stripping effectively induced both CD4 and CD8 T cell responses in humans, offering a promising alternative to intramuscular injection.
January 2023 in “Open veterinary journal” This study observed that applying a cream containing secretome from Bovine Umbilical Vein Endothelial Cells promoted healing and regeneration in burn wounds in rats, particularly at a 15% concentration.
7 citations
,
November 2020 in “Journal of Tissue Viability” In this study, follicular unit extraction grafting using a patient's own scalp follicles showed promise in healing chronic ulcers in a woman with recessive dystrophic epidermolysis bullosa.
6 citations
,
January 1990 in “The Journal of Dermatology” This study successfully developed a method to culture human hair follicle cells without a biological feeder layer, maintaining cell differentiation for a month.
28 citations
,
March 2010 in “Histochemistry and Cell Biology” This study identified specific markers that can distinguish between stem cells in different regions of human scalp hair follicles, offering potential strategies for cell sorting and purification based on these markers.
7 citations
,
January 2016 in “Methods in molecular biology” This study describes the process of isolating and analyzing multipotent stem cells from mouse hair follicles for potential use in tissue engineering and regenerative medicine.
3 citations
,
January 2020 in “Journal of Cutaneous and Aesthetic Surgery” This review highlighted that despite existing treatments, chronic nonhealing leg ulcers remain a significant therapeutic challenge, necessitating the development of new methods that are effective, safe, and affordable for patients.
2 citations
,
July 2022 in “The Kaohsiung Journal of Medical Sciences” This study demonstrated that the immunomodulatory drug FTY720 may enhance the survival of allogeneic fat grafts in mice by reducing immune rejection and improving neovascularization.
4 citations
,
August 2024 in “Health Science Reports” This study found that using hair follicle units to treat hard-to-heal wounds led to complete or partial closure in most patients, with reduced operation time, minimal morbidity, and low complication rates and costs.
July 2004 in “Journal of Clinical Oncology” This study found therapeutic isolated limb perfusion with melphalan to be effective for in-transit melanoma metastases on a limb, with a high response rate and transient systemic toxicity.
15 citations
,
February 2011 in “Journal of Tissue Engineering and Regenerative Medicine” This study found that a newly developed hemi-vascularized sandwich method significantly improved the regeneration and maturity of hair follicles compared to other transplantation approaches in rat models.
1 citations
,
October 2020 in “Journal of Investigative Dermatology Symposium Proceedings” This study found that platelet-rich plasma treatment increased hair density and reduced inflammation in patients with patchy alopecia areata, but not in a patient with alopecia universalis.
19 citations
,
May 2016 in “Cytotechnology”
January 2021 in “Research Square (Research Square)” This study found that repeated plateletpheresis had no significant effect on whole blood cells and plasma proteins in donors, maintaining levels within a normal range.
September 2022 in “British Dental Journal” Platelet-rich fibrin is becoming popular for medical and cosmetic uses like hair growth and natural fillers.
September 1997 in “Dermatologic Surgery” This article reviews different grafting strategies for hair restoration surgery in extensive baldness and suggests uniform density grafting offers less detectable results, especially under adverse grooming conditions.
June 2025 in “Cancer Management and Research” This study found that scalp cooling resulted in visible hair retention in 53% of breast cancer patients undergoing Epirubicin/Cyclophosphamide and Paclitaxel treatment, with factors like hair bulb diameter, shaft diameter, and anagen rate significantly predicting outcomes.
5 citations
,
January 2015 in “Skin appendage disorders” This study found that pigmented hair-thickening fibers improved the appearance of scalp alopecia in patients with epidermolysis bullosa, although they may cause pruritus and should be used cautiously.
July 2004 in “Journal of Clinical Oncology” This study found that therapeutic isolated limb perfusion with melphalan for in-transit melanoma metastases resulted in a high response rate but was associated with some systemic toxicity, including nausea, vomiting, and transient bone marrow depression.
6 citations
,
June 2017 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” This study reported that using hair follicles from the scalp in punch-type grafts improved healing in chronic venous ulcers compared to traditional hairless punch grafts.
September 2025 in “Journal of the Egyptian Womenʼs Dermatologic Society” This study found that using platelet-rich plasma as a storage solution in follicular unit extraction hair transplantation significantly improved hair regeneration, density, and graft quality compared to normal saline.
1 citations
,
October 2023 in “European Journal of Dermatology” This study found that combining hair transplantation with platelet-rich plasma treatment significantly improved hair regeneration, reduced hair loss, and minimized skin lesion areas in patients with androgenic alopecia compared to hair transplantation alone, suggesting enhanced treatment efficacy.
January 2023 in “Skin appendage disorders” This review discusses the scalp microinfusion MMP® technique for hair loss treatment and reports no new results; it emphasizes the need for more standardized studies.