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This study identifies various phytochemicals in Thuja orientalis bark, potentially aiding its botanical identification and quality standardization.

This study found that microbial transformation of dihydrotestosterone with two types of fungi produced eight metabolites, among which metabolites 5–7 were significant inhibitors of butyrylcholinesterase, suggesting potential in Alzheimer's disease management.

This study developed a new method for synthesizing finasteride that eliminates the need for expensive and toxic chemicals, achieving high purity and a 24.2% yield.

The abstract discusses that Serenoa repens, a commonly used phytotherapeutic agent, may play a crucial role as an alternative or complementary treatment for lower urinary tract symptoms in patients with benign prostatic hyperplasia, particularly those with mild-to-moderate disease severity.

This study reported that phytochemicals SA-4 and SA-6 from Tridax procumbens exhibited a dose-related immunostimulatory effect on mice, suggesting their potential as immunostimulators.

This review discusses the development and potential therapeutic effects of nitroxide small molecule agents for age-related macular degeneration and cardiovascular disease, but reports no new clinical results.

This study developed an inexpensive method to provide initial data on both the photostability and toxicity of pure active principles and their photodegradation products.

This study developed a simple and cost-effective chromatographic method for simultaneously analyzing betamethasone dipropionate and calcipotriol, achieving rapid separation within 7 minutes suitable for routine applications.

This study found that emodin from Polygonum multiflorum showed 5alpha-reductase inhibitory activity, which was more potent than alizarin but less potent than riboflavin.

This study developed chemical fingerprints to differentiate Eclipta prostrata and Wedelia calendulacea, two plants often confused and adulterated in the Indian herbal market, identifying distinct chemical profiles that can prevent such adulteration.

This study identified distinct and significant adverse event patterns across different drug classes used to treat benign prostatic hyperplasia, confirming known risks and suggesting novel safety signals for further investigation.

This study discovered that the disposition of LY191704 enantiomers in rats and dogs is both stereoselective and species specific.

This article lists the clinically important interactions and skin reactions of several drugs and substances, including THA, FK506, tamoxifen, tamsulosin, tartrazine, tea tree oil, temazepam, and temozolomide, but provides no new clinical results.

This study reports that the dye peri-xanthenoxanthene (PXX) can act as an efficient photocatalyst for various radical reactions, including complex dual catalytic processes and the synthesis of an investigational drug intermediate.

This study found that using headspace capillary gas chromatography effectively determined the levels of residual organic solvents, including chloroform and dichloromethane, in finasteride with good separation and detection limits.

This study reports that difluoromethyl nitrile oxide can rapidly functionalize various alkenes at room temperature, leading to products that can transform into valuable medicinal chemistry building blocks like CF2H-isoxazolines for bioactive molecule modification.

In this study, exposure to m-Aminophenol in human keratinocytes altered the expression of thousands of genes involved in inflammation and stress responses, suggesting potential biomarkers for MAP-induced skin toxicity.

This study found that extracts from the plant Platycodon grandiflorum, particularly the butanol extract, demonstrated potential in preventing hair loss by showing significant antioxidant activity, promoting cell proliferation, and inhibiting inflammation in various cell models.

This study demonstrated that FT-Raman spectroscopy is effective for identifying finasteride polymorphs in tablets and detecting the presence of alternative polymorphs down to about 15% concentration.

This study found that some synthesized 17-oximino-5-androsten-3β-yl esters demonstrated stronger cytotoxicity and antiandrogenic activity against prostate cancer cells than finasteride.

In this study, researchers developed a new Supported Ionic Liquid Phase palladium catalyst that showed effectiveness in aminocarbonylation reactions for synthesizing pharmaceutical compounds like CX-546 and a precursor of Finasteride, though results were sensitive to substrate variations and prompted palladium leaching concerns.

This report adds two cases of total ovarian pigmentation, with no associated symptoms or pathological findings, to the previously reported unilateral case.

This article reviews guidelines and medications for treating benign prostatic hyperplasia but presents no new clinical results.

This study found that solid-state NMR combined with X-ray techniques provided critical insights into the structure and solvation of finasteride polymorphs, identifying gaps in existing patent characterizations.

This case report describes a patient with chronic renal failure on hemodialysis who experienced hair depigmentation while taking heptaminol, with the condition reversing after discontinuing the medication; the exact mechanism causing the color change is still unclear.

This study found that a phytosome lotion made from Mangkokan leaf extract, using a green solvent and microwave-assisted extraction, demonstrated greater hair growth activity than 2% minoxidil, with the 30% phytosome lotion showing the highest efficacy in increasing hair length, weight, and diameter.

In this study, 12-Chloracetyl-PPD showed anti-cancer activity by inhibiting cancer cell viability and inducing apoptosis through reactive oxygen species production without harming normal cells.

0.1% piroctone olamine in hair tonics effectively treats dandruff.

This study found that minoxidil increased plasma renin activity in patients with hypertension through both an adrenergic mechanism related to heart rate changes and a secondary mechanism unrelated to propranolol.