Photostability and Toxicity of Finasteride, Diclofenac, and Naproxen Under Simulated Sunlight Exposure: Evaluation of the Toxicity Trend and Packaging Photoprotection

    December 2013 in “ Chemistry Central Journal ”
    Maria Pia Sammartino, Mauro Castrucci, D. Ruiu, Giovanni Visco, Luigi Campanella
    Image of study
    TLDR Sunlight exposure increases drug toxicity; amber glass best for protection.
    This study evaluated the photostability and toxicity of three drugs, finasteride, diclofenac, and naproxen, under simulated sunlight exposure. The drugs were photodegraded and their toxicity increased after exposure to sunlight. The study also evaluated the effectiveness of different packaging materials in protecting the drugs from sunlight exposure and found that amber glass was the most effective. The findings suggest that the photodegradation of these drugs in the environment may increase their toxicity and that proper packaging can help mitigate this effect.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 1000+ results

      community Well here I am 3-4 years later.

      in Update  56 upvotes 2 years ago
      The conversation is about someone who has been taking finasteride for hair loss without success, considering switching to dutasteride or giving up treatment. Suggestions include trying dutasteride, microneedling, infrared therapy, multivitamins, and high-concentration topical solutions combining finasteride and dutasteride.

      community Drastic and sudden change in hair loss condition

      by OrlandoS in General  76 upvotes 1 year ago
      The user experienced increased hair loss and scalp itchiness despite using finasteride and plans to resume minoxidil and start microneedling. They are considering using clay, Aveda thickening tonic, and a beanie to manage the appearance of thinning hair.

      community Hair Loss Drugs Ranked in Order of Efficacy

      in Research/Science  67 upvotes 2 years ago
      Dutasteride is likely the most effective treatment for male pattern baldness, followed by finasteride and minoxidil in various forms and dosages. Users discuss personal experiences, dosages, and potential side effects, with some considering combining treatments for better results.
      Do i hop on finasteride and minoxidil?

      community Do i hop on finasteride and minoxidil?

      by Taylor in General  71 upvotes 3 months ago
      The user is concerned about hair loss and considering using finasteride and minoxidil after a doctor suggested a steroid for a dry scalp. They are worried the steroid won't prevent further hair loss.

      community Finasteride before and after 6 years

      in Progress Pictures  227 upvotes 1 year ago
      A user shared progress pictures after 6 years of using finasteride, showing maintained hair with no regrowth. Suggestions included possibly adding minoxidil and switching to dutasteride for better results.

    Related Research

    2 / 2 results