research Targeting the Wnt Pathways for Therapies
Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
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research The Roles of Wnt/β-Catenin Pathway in Tissue Development and Regenerative Medicine
The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.
research The Role of Pannexin 3 in Bone Biology
Pannexin 3 is important for bone formation and the development of bone cells.
research Diagnostic Approach to Low-Renin Hypertension
Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.
research Combined Oral Contraception and Bicalutamide in Polycystic Ovary Syndrome and Severe Hirsutism: A Double-Blind Randomized Controlled Trial
Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.
research The Role of R-Spondins and Their Receptors in Bone Metabolism
R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.
research Molecular Genetics of Keratinization Disorders: What's New About Ichthyosis
Over 67 genes linked to ichthyosis help improve diagnosis and treatment.
research Molecular Pathology of Skin Adnexal Tumors
New markers and pathways have been found in skin tumors, helping better understand and diagnose them.
research Dovobet Ointment Under Occlusion Overnight for Troublesome Scalp Psoriasis
Dovobet ointment used overnight effectively reduces scalp psoriasis severity and itch.
research Role of Environmental Factors and Gonadotoxin Exposure in Unexplained Male Infertility
Environmental factors and exposure to toxins may contribute to male infertility by affecting sperm and hormone function.
research Calcipotriene Plus Betamethasone Dipropionate Gel: A New Combination Therapy for Scalp Psoriasis
The new gel combining calcipotriene and betamethasone is effective and safe for treating scalp psoriasis.
research Illuminating Microflora: Shedding Light on the Potential of Blue Light to Modulate the Cutaneous Microbiome
Blue light might help treat skin conditions by affecting the skin's bacteria.
research Systemic Antifungals: Overview, Applications, and Costs
Terbinafine is the most effective medicine for fungal nail infections, especially for diabetics and those with weak immune systems.
research Oral Presentations: Findings from Dermatological Studies
The document concludes that an experimental drug may help wound healing in Epidermolysis Bullosa, links Hydroa vacciniforme to EBV, discusses diagnosing hair loss disorders, finds many children with eczema have allergies, reviews the safety of a skin medication in children, notes side effects of a Duchenne's treatment, and identifies a marker for pediatric mastocytosis.
research Adverse Effects Associated with Long-Term Administration of Azole Antifungal Agents
Long-term use of azole antifungals can cause hair loss, hormonal imbalances, and severe skin reactions.
research Loss of Epidermal Evi/Wls Results in a Phenotype Resembling Psoriasiform Dermatitis
Loss of a specific protein in skin cells causes symptoms similar to psoriasis.
research Cell Death in Skin Function, Inflammation, and Disease
Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.
research The Origins of Skin Diversity: Lessons From Dermal Fibroblasts
New research shows that skin diversity is influenced by different types of dermal fibroblasts and their development, especially involving the Wnt/β-catenin pathway.
research Cardiac and Renal SARS-CoV-2 Viral Entry Protein Regulation by Androgens and Diet: Implications for Polycystic Ovary Syndrome and COVID-19
Androgens and a high-fat diet may increase the risk of severe COVID-19 in women with PCOS by upregulating certain proteins in the heart and kidneys.
research TRPV3 Ion Channel: From Gene to Pharmacology
The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.
research Research Techniques Made Simple: Optical Clearing and Three-Dimensional Volumetric Imaging of Skin Biopsies
3D imaging of skin biopsies offers better accuracy but is time-consuming and can't clear melanin.
research Neurobiology, Stem Cell Biology, and Immunology: An Emerging Triad for Understanding Tissue Homeostasis and Repair
The nervous system helps control stem cell behavior and immune responses, affecting tissue repair and maintenance.
research Prescribing Patterns Amongst UK Dermatologists for the Treatment of Alopecia Areata, Female Pattern Hair Loss, and Frontal Fibrosing Alopecia
UK dermatologists commonly use corticosteroids and minoxidil to treat hair loss conditions.
research The British Hair And Nail Society Present A Review Of Our National Grand Round Of Challenging Hair Disorders And The Benefits To The Wider British Association Of Dermatologists Membership
The grand round helps improve diagnoses and suggests new treatments for hair disorders.
research The British Hair and Nail Society Presents a Review of Our National Grand Round of Challenging Hair Disorders and the Benefits to the Wider British Association of Dermatologists Membership
The review helps improve diagnosis and treatment of challenging hair disorders.
research Defining Pseudofolliculitis Barbae in 2001: A Review of the Literature and Current Trends
Pseudofolliculitis barbae is a chronic skin condition affecting mainly African American and Hispanic individuals, caused by shaving tightly curled hair, and managed by prevention and treatment but not curable.
research Characterization and Chromosomal Localization of Human Hair-Specific Keratin Genes and Comparative Expression During the Hair Growth Cycle
Two specific hair keratin genes are active during hair growth and decline as hair transitions to rest.
research The Human Type II Keratin Gene Cluster on Chromosome 12q13.13: Final Count or Hidden Secrets?
The document concludes that the human keratin gene cluster is complex, with a need for updated naming to reflect over 50 functional genes important for hair and skin biology.
research Guidelines of Care for the Management of Acne Vulgaris
Use benzoyl peroxide, retinoids, antibiotics, and isotretinoin for acne, and combine treatments for better results.
research Sequence and Expression of Human Hair Keratin Genes
Human hair keratin genes are similar to mouse genes and are specifically expressed in hair follicles.