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A young Saudi girl with uncontrolled type 1 diabetes and hypothyroidism had two rare conditions, Mauriac syndrome and Van Wyk–Grumbach syndrome.

Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.

Odontogenic keratocysts are caused by abnormal Hedgehog signaling and can lead to tooth and bone issues.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.

Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.

Pubertal acne is linked to hormonal changes, affects quality of life, and is treated similarly to adult acne.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.

LPA3 signaling in the uterus is crucial for placental formation and fetal development.

Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.

Catalytic antibodies are early indicators and active participants in the development of systemic lupus erythematosus.

New treatments for hair loss may target specific pathways and generate new hair follicles.

High Nesfatin-1 and low Vitamin D may increase blood pressure and heart rate in women with PCOS.

The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.

Hormone treatment for transsexual individuals is effective but carries risks like thromboembolic events and mood changes, with most side effects being minor and reversible.

The document concludes that more multidisciplinary research is needed to understand and treat PCOS, a condition that significantly affects women's health and quality of life.

QMSI is a valuable method for studying drug penetration in skin tissues.

The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

MALDI Imaging Mass Spectrometry is a useful method for studying skin conditions, but sample preparation is crucial for accurate results.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.

Centrosomes are essential for healthy skin and hair growth, and their role is different from that of cilia.

Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

Coats' Plus is a genetic disorder with eye abnormalities, brain calcification, poor growth, bone and skin issues, and movement disorders.

Daughters of women with PCOS generally experience normal puberty but may have more body hair and different body fat distribution.

Higher fluoride levels may delay puberty in boys.

The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.

LAAM caused developmental toxicity in tolerant rats without causing birth defects.