695 citations
,
October 2011 in “Cell stem cell” This review discusses the metabolic and physiological mechanisms that maintain hematopoietic stem cell function, particularly focusing on oxygen and energy homeostasis, but it reports no new experimental results.
187 citations
,
April 2019 in “npj Regenerative Medicine” This study found that hMSC secretomes from umbilical cord Wharton's jelly had the most potent angiogenic effects, whereas those from adipose tissue demonstrated the weakest angiogenic potential.
89 citations
,
August 2013 in “PloS one” This study used the "ARE-Luc" mouse model to visualize androgen receptor activity across various tissues in both male and female mice, highlighting the direct action of androgens outside reproductive organs.
76 citations
,
January 2017 in “World Journal of Stem Cells” This review discusses the potential applications of adipose-derived stromal cells for treating conditions like colitis, liver failure, and more, without presenting new clinical results.
34 citations
,
January 2013 in “Frontiers in genetics” This review discusses how certain adult stem cells can produce factors that support the maintenance of other stem cell populations within shared niches, and it reports no new experimental results.
30 citations
,
January 2007 This article reviews the use of cyclophosphamide in kidney disease treatment, highlighting significant concerns about long-term risks of cancer and infertility, and stress strategies for dose reduction and side effect mitigation; no new study results are presented.
29 citations
,
December 2021 in “Biomedicines” This study found that exosomes from different mesenchymal stem cell sources had distinct effects on immune cell functions and varied microRNA expression profiles compared to their original cells.
20 citations
,
November 2021 in “Biomedicines” This review examines the potential of adipose-derived stem cells in disease treatment and highlights the need for further research to clarify their effectiveness and safety.
12 citations
,
January 1988 in “Toxicology and Applied Pharmacology” Minoxidil promotes hair growth without causing DNA damage.
3 citations
,
January 2023 in “Journal of Hard Tissue Biology” This study found that Wnt10a expression in odontoblasts increased with dental pulp regeneration and may be a potential non-cellular agent for inducing dental pulp regeneration with dentine-inducing capacity.
3 citations
,
January 2017 in “Stem Cells International” This article highlights the significant challenge that tissue regeneration presents to modern medicine, emphasizing its importance in improving quality of life.
3 citations
,
January 2011 in “American Journal of Hematology” This study describes a case where immunochemotherapy, including chlorambucil and rituximab, successfully reversed agranulocytosis and other Waldenström's macroglobulinemia symptoms, indicating a possible connection between the two.
3 citations
,
October 2001 in “British Journal of Ophthalmology” This case report suggests that intralesional cidofovir successfully treated SCC without systemic toxicity, making it a potential alternative to consider alongside surgical excision.
2 citations
,
January 2013 in “Journal of the Korean Association of Oral and Maxillofacial Surgeons” This review discusses the potential of dental tissues as an alternative source of adult stem cells for regenerative medicine but reports no new experimental results, emphasizing the need for effective preservation methods.
1 citations
,
September 2025 in “International Journal of Molecular Sciences” This study found that primary stem cells from concentrated growth factor can differentiate into adipogenic, endothelial, and neuronal lineages in vitro, suggesting potential for use in regenerative therapies.
November 2025 in “Stem Cell Research & Therapy” This study suggests that human DSCCs may aid in hair follicle regeneration and reduce microinflammation, with potential applications in regenerative medicine evaluated through a new morphometric analysis.
January 2022 in “International Journal of Medical Research” This article discusses the negative impact of chemotherapy on healthy cells, noting side effects like decreased blood cell production and hair loss, but reports no new findings.
December 2017 in “Revista da Sociedade Portuguesa de Dermatologia e Venereologia” This report describes a case where a woman developed permanent alopecia after chemotherapy with taxanes for breast cancer, and she showed favorable response to 6 months of minoxidil topical treatment.
January 2016 in “Chemistry & Industry” This article discusses various aspects of hair loss but reports no new research findings.
January 2015 in “Elsevier eBooks” This review discusses the potential of stem cell-based therapies combined with artificial nerve grafts for improving recovery in animal models of severe peripheral nerve injury, highlighting the need for further research on their application to humans.
February 2009 in “Journal of The American Academy of Dermatology” Certain immune system genes are linked to a higher risk of psoriasis and psoriatic arthritis, while others may offer protection.
June 2024 in “International Journal of Research in Ayurveda and Pharmacy” This study explores Ayurvedic concepts for hair conditions such as hair loss, premature greying, alopecia areata, seborrheic dermatitis, and dandruff, highlighting treatments that include Panchakarma and Rasayana medicines for potential relief.
38 citations
,
February 2023 in “International Journal of Advanced Research in Science Communication and Technology” This article reviews plant-based secondary metabolites with potential anticancer properties and highlights the need for new treatments due to the side effects of current cancer therapies, but it provides no clinical results.
254 citations
,
January 2012 in “Nature Reviews Molecular Cell Biology” This review discusses the role of stem cell progeny as integral components of stem cell niches, offering feedback that may influence different stem cell systems' microenvironments, but it presents no new research findings.
186 citations
,
February 2017 in “Cell Proliferation” This review suggests that omitting the proteolysis step and including tissue pieces in mesenchymal stem cell isolation may improve cell quality, reduce contamination risk, and lower costs and processing time in clinical applications.
126 citations
,
January 2001 in “World Journal of Surgery” This review discusses current treatment options for liver hydatidosis, noting the potential benefits and limitations of chemotherapy and highlighting the need for more clinical trials to prevent recurrent disease; it reports no new findings.
106 citations
,
August 2021 in “Pharmaceuticals” This review discusses the role of extracellular vesicles in wound healing and explores their potential applications in skin repair and treatment of dermal diseases, reporting no new clinical findings.
85 citations
,
April 2007 in “Dermatologic Clinics” This article reviews drug-induced hair changes, highlighting that while many drugs are occasionally linked to hair loss, this connection has been conclusively established for only a few, and such hair loss is typically reversible.
77 citations
,
November 2018 in “Cell” Lung immune cells can be trained to better fight infections after a virus.
63 citations
,
April 2010 in “Development” This article discusses the bi-compartmental organization of hair follicle stem cell niches for balancing stem cell cycling and organ growth and proposes similar structures may exist in other adult stem cell niches but reports no new experimental results.