May 2005 in “Molecular Carcinogenesis” This study found that mrp/plf-mRNA expression in murine skin increases in response to different tumor promoters, suggesting its potential as a short-term biomarker for chemical carcinogenesis.
3 citations
,
August 2013 in “Maǧallaẗ ǧāmiʻaẗ al-anbār li-l-ʻulūm al-ṣirfaẗ” This study found that women with polycystic ovary syndrome had significantly lower levels of estradiol and follicle stimulating hormone compared to fertile women, with no significant differences in testosterone and thyroid hormone levels.
11 citations
,
January 2016 in “Evidence-based Complementary and Alternative Medicine” This study found that rice bran ash extract and orthosilicic acid both increased melanin synthesis and related protein expression in melanocytes, suggesting potential therapeutic use for melanin deficiency.
22 citations
,
June 1993 in “Calcified Tissue International” This study found that women with hyperandrogenic amenorrhea do not show reduced bone mineral density compared to controls, indicating they may be protected from osteopenia.
28 citations
,
March 2020 in “Journal of ethnopharmacology” This study found that ginsenoside Rb1 treatment significantly reduced aging symptoms in mice by regulating cell cycle and apoptotic pathways, potentially linked to metabolic changes.
In this study, melatonin implantation altered BMP2 gene expression associated with hair follicle growth in Inner Mongolia Cashmere Goats, particularly reducing expression during the follicles' resting period.
April 2024 in “International journal of molecular sciences” This narrative review discusses the promising role of photobiomodulation in dermatology, emphasizing its non-invasive nature and potential benefits, but acknowledges the need for further research to establish standard protocols.
July 2023 in “International Journal of Molecular Sciences” In this study, Trapa bispinosa Roxb. pericarp extract demonstrated inhibitory effects on 5α-reductase activity both in vitro using LNCaP cells and in vivo in a mouse model of benign prostatic hyperplasia, suggesting its potential role in managing the condition.
218 citations
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October 2013 in “Proceedings of the National Academy of Sciences of the United States of America” This study found that removing PPARγ specifically from mouse adipose tissue led to severe fat loss, insulin resistance, diabetes, and associated metabolic abnormalities.
August 2017 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” In this study, melatonin supplementation in cattle during mid to late gestation decreased the temperature of unshaved skin areas but did not affect rectal temperature or body weight.
33 citations
,
May 2017 in “Journal of Clinical Oncology” This phase I study reported that ETC-159, targeting Wnt signalling, showed tolerable safety profiles at doses that inhibit its pathway, though bone turnover markers increased, warranting early and regular monitoring. No tumor responses were observed, but two patients achieved stable disease for several cycles.
3 citations
,
March 2022 in “Journal of Infection” This study observed that SARS-CoV-2 shedding significantly decreased after remdesivir treatment, irrespective of RT-PCR cycle threshold values, suggesting early de-isolation might be possible in severe COVID-19 cases.
2 citations
,
March 2022 in “Applied sciences” In this study, Lespedeza bicolor extract was found to enhance dermal papilla cell proliferation and extend the anagen phase in mice, suggesting its potential as a treatment for alopecia.
1 citations
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April 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study identified the NAC transcription factor RD26 as a critical regulator of drought-induced root hair growth restriction in Arabidopsis thaliana, with a similar mechanism observed in tomatoes, indicating evolutionary conservation.
1 citations
,
February 2024 in “Peer Review” This study reviewed the use of rosemary essential oil combined with photobiomodulation for treating androgenetic alopecia, highlighting the potential benefits of rosemary's antioxidant and vasodilatory properties alongside enhanced cellular processes from photobiomodulation.
29 citations
,
April 2019 in “Acta neuropathologica communications” This study found that β-sitosterol, a brain-penetrable phytosterol, reduced melanoma cell growth and brain metastasis formation by interfering with mitochondrial respiration, suggesting its potential as an adjuvant therapy to BRAF inhibitors for patients with melanoma brain metastases.
42 citations
,
May 2009 in “Contraception” This study found that the combined oral contraceptive containing ethinyl estradiol and chlormadinone acetate was effective in reducing moderate papulopustular acne and other androgen-related skin disorders compared to placebo.
November 2019 in “Neuro-oncology” This study found that using rind-based dosimetric techniques in brain irradiation significantly reduced scalp dose and alopecia compared to standard treatment plans, with 60% of patients experiencing no hair loss.
January 2006 in “Advances in developmental biology” This review discusses the roles of the hairless (HR) protein as a corepressor, particularly its impact on RORα-mediated transcriptional repression, and reports no new experimental findings.
11 citations
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October 2018 in “Hormone and Metabolic Research” This study found no difference in bone mineral density between young women with PCOS and age- and BMI-matched controls, but BMI significantly influenced BMD in women with PCOS.
April 2012 in “The Journal of Urology” This meta-analysis reported that dietary intake of omega-3 or omega-6 fatty acids does not significantly impact prostate cancer risk.
12 citations
,
August 2015 in “Experimental Dermatology” This study indicated that the mineralocorticoid receptor (MR) plays a transient role in regulating epidermal differentiation during late embryonic stages, with glucocorticoid receptor (GR) potentially compensating for MR loss during the perinatal period.
4 citations
,
October 2018 in “International Braz J Urol” This study found no positive association between the use of 5α-reductase inhibitors and the risk of male breast cancer.
June 2025 in “Archives of Dermatological Research” This study found that photobiomodulation-irradiated conditioned medium from human adipose-derived stromal cells enhanced hair growth in mice, suggesting its potential as a treatment for hair loss by increasing growth factor secretion.
6 citations
,
October 2019 in “Jo'jig gonghag gwa jaesaeng uihag/Tissue engineering and regenerative medicine” This study found that rice bran ash extract enhanced melanin biosynthesis-related protein expression in a 3D hair follicle-like tissue model and hair follicle organ culture, suggesting potential for future research in melanogenesis.
70 citations
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February 2009 in “Biological Trace Element Research” May 2019 in “Asian Journal of Pharmaceutical and Clinical Research” This study found a significant association between unhealthy food patterns and higher BMI in young women with PCOS, emphasizing the need for awareness of lifestyle's impact on hormonal and metabolic health.
34 citations
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September 2019 in “Clinical, Cosmetic and Investigational Dermatology” This review covers the use of photobiomodulation devices for hair regrowth in various types of alopecia and reports no new clinical results.
September 2023 in “Journal of the American Academy of Dermatology” This study discusses calcinosis cutis and alopecia totalis, highlighting the need for thyroid disease screening in children with alopecia areata, especially those with a history of Down syndrome or signs of potential thyroid dysfunction.
May 2025 in “Research Square (Research Square)” This study found that conditioned medium from photobiomodulation-irradiated adipose-derived stromal cells enhanced hair growth in a mouse model of hair loss more effectively than non-irradiated medium, suggesting potential for treating alopecia by boosting growth factor secretion.