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    Subcutaneous Injection of Conditioned Medium from Photobiomodulation-Treated Adipose-Derived Stromal Cells Promotes Hair Growth in Mice

    May 2025 in “ Research Square (Research Square) ”
    In‐Su Park

    Preprint — not peer reviewed. This was posted to a preprint server or data repository. It has not been through a journal's review process, and its findings may change or not hold up.

    Studysummary This study found that conditioned medium from photobiomodulation-irradiated adipose-derived stromal cells enhanced hair growth in a mouse model of hair loss more effectively than non-irradiated medium, suggesting potential for treating alopecia by boosting growth factor secretion.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 14

    1. The Hormonal Background of Hair Loss in Non-Scarring Alopecias Biomedicines · 2024
    2. Hypoxia Enhances the Hair Growth-Promoting Effects of Embryonic Stem Cell-Derived Mesenchymal Stem Cells Via NADPH Oxidase 4 Biomedicine & Pharmacotherapy · 2023
    3. Integrative and Mechanistic Approach to the Hair Growth Cycle and Hair Loss Journal of Clinical Medicine · 2023
    4. Regenerative Medicine Strategies for Hair Growth and Regeneration: A Narrative Review of Literature Regenerative Therapy · 2022
    5. Treatment Options for Androgenetic Alopecia: Efficacy, Side Effects, Compliance, Financial Considerations, and Ethics Journal of Cosmetic Dermatology · 2021
    6. Functional Hair Follicle Regeneration: An Updated Review Signal Transduction and Targeted Therapy · 2021
    7. Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development Cells · 2019
    8. Review of Quality of Life Studies in Women with Alopecia International Journal of Women's Dermatology · 2018
    9. Treatment of MSCs with Wnt1a-Conditioned Medium Activates DP Cells and Promotes Hair Follicle Regrowth Scientific Reports · 2014
    10. An Overview of Alopecias Cold Spring Harbor Perspectives in Medicine · 2014
    11. Ultraviolet B Preconditioning Enhances the Hair Growth-Promoting Effects of Adipose-Derived Stem Cells Via Generation of Reactive Oxygen Species Stem Cells and Development · 2012
    12. PDGF Isoforms Induce and Maintain Anagen Phase of Murine Hair Follicles Journal of Dermatological Science · 2006
    13. Burden of Hair Loss: Stress and the Underestimated Psychosocial Impact of Telogen Effluvium and Androgenetic Alopecia Journal of Investigative Dermatology · 2004
    14. Promoted Growth of Murine Hair Follicles Through Controlled Release of Vascular Endothelial Growth Factor Biomaterials · 2002