Effects of Exogenous Melatonin on the Gene Expression of BMP2 in the Skin of Inner Mongolia Cashmere Goat

    January 2013
    Su Ru
    TLDR Melatonin reduces BMP2 gene expression in goat hair follicles during the resting period.
    The study investigated the effects of melatonin (MT) on the expression of the BMP2 gene in the hair follicles of Inner Mongolia Cashmere Goats. Eight female goats were divided into four groups, with three groups receiving MT implants and one serving as a control. Over a year, BMP2 gene expression was measured using real-time quantitative PCR. Results indicated that BMP2 expression increased slowly during both the prosperous and resting periods of hair follicle development, with higher expression in the resting period. MT implantation reduced BMP2 expression during the resting period, but there was no significant difference in expression throughout the entire growth period. The study suggested that BMP2 might play a role in regulating hair follicle growth and development in these goats.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 259 results

      community Is anyone using melatonin for hair loss?

      in Research/Science  9 upvotes 6 months ago
      Melatonin is being discussed as a potential treatment for hair loss, with questions about its effectiveness and whether it should be used topically or orally. No specific conclusions or personal experiences were shared.

      community Melatonin options for Europe??? *Retrograde Alopecia*

      in Product  3 upvotes 7 months ago
      A user is considering using melatonin for hair recovery on the side and neck area but is unsure about the best options in Europe and whether a dietary supplement form can be applied to the scalp. They found a product but are hesitant and seeking opinions on its use for alopecia.

      community Optimal dose for topical Melatonin

      in Treatment  6 upvotes 1 year ago
      The conversation is about finding the optimal concentration of topical melatonin for hair loss treatment. The user is considering making their own solution and is unsure whether a higher concentration is more effective for deactivating prolactin receptors.

      community Compounding Topical Melatonin at Home

      in Treatment  8 upvotes 3 years ago
      Melatonin at a 0.0033% concentration shows results for hair loss when used topically. A user is discussing how to replicate this by adding 2mg of Melatonin to 60ml of Minoxidil solution.

      community Melatonin a possible tool to help fight AGA hair loss.

      in Research/Science  50 upvotes 3 years ago
      Topical melatonin may help reduce hair loss and increase hair thickness in people with androgenetic alopecia (AGA), with some studies showing positive results. It can be mixed with minoxidil for application, and its effectiveness might be enhanced when used with micro-needling, but results may vary among individuals.

    Related Research

    5 / 5 results