Effects of Exogenous Melatonin on the Gene Expression of BMP2 in the Skin of Inner Mongolia Cashmere Goat
January 2013
New to Melatonin? There is a guide in the encyclopedia. Read the guide → Studysummary In this study, melatonin implantation altered BMP2 gene expression associated with hair follicle growth in Inner Mongolia Cashmere Goats, particularly reducing expression during the follicles' resting period. Our plain-language summary of this paper — not a Tressless recommendation.
The study investigated the effects of melatonin (MT) on the expression of the BMP2 gene in the hair follicles of Inner Mongolia Cashmere Goats. Eight female goats were divided into four groups, with three groups receiving MT implants and one serving as a control. Over a year, BMP2 gene expression was measured using real-time quantitative PCR. Results indicated that BMP2 expression increased slowly during both the prosperous and resting periods of hair follicle development, with higher expression in the resting period. MT implantation reduced BMP2 expression during the resting period, but there was no significant difference in expression throughout the entire growth period. The study suggested that BMP2 might play a role in regulating hair follicle growth and development in these goats.
