11 citations,
July 2014 in “Gene” The S250C variant in a gene may cause autoimmunity and immunodeficiency by impairing protein function.
3 citations,
April 2021 in “Journal of Medicinal Chemistry” Finasteride may affect PNMT, causing side effects.
1 citations,
May 2022 in “IntechOpen eBooks” Obesity leads to physical, metabolic, reproductive issues, higher healthcare costs, and mental health problems.
1 citations,
December 2020 in “International journal of molecular sciences” External factors can cause skin cancer cells that usually don't spread to grow and form tumors in mice.
2 citations,
February 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” The Asiatic lion has very low genetic diversity and unique genetic traits, highlighting the need for its conservation.
2 citations,
March 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Hairless mammals have genetic changes in both their protein-coding and regulatory sequences related to hair.
143 citations,
January 2007 in “The American Journal of Human Genetics” Certain genes on chromosomes 6, 10, 16, and 18 may increase the risk of alopecia areata.
3 citations,
March 2020 in “Dermatology Research and Practice” Tracnil™, a mix of myo-inositol, folic acid, and vitamin D3, safely reduced acne, improved excessive hair growth, and fixed irregular periods in overweight women with PCOS.
44 citations,
October 2019 in “International Journal of Molecular Sciences” Melatonin, usually known for sleep regulation, also has antioxidant properties that can protect skin, stimulate hair growth, and improve skin conditions, with topical application being more effective than oral use.
21 citations,
September 2019 in “Archives of Physiology and Biochemistry” High-intensity interval training improves certain hormone levels and lipid profiles in women with PCOS.
17 citations,
September 2017 in “Journal of Cosmetic Dermatology” Women with PCOS in North China often have hirsutism and acne, with hirsutism linked to metabolic issues.
July 2024 in “Gene & Protein in Disease” Exosome therapy shows promise for treating skin conditions and improving wound healing.
19 citations,
November 2021 in “Reviews in endocrine and metabolic disorders” Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.
24 citations,
July 2019 in “Journal of Obstetrics and Gynaecology” The combination therapy improved PCOS symptoms in both obese and non-obese women, with weight loss in the obese group.
12 citations,
December 2018 in “Clinical Ophthalmology” Latanoprostene bunod effectively lowers eye pressure and is better tolerated than other glaucoma medications.
21 citations,
January 2020 in “General and Comparative Endocrinology” Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
49 citations,
March 2019 in “Journal of Investigative Dermatology” Skin fat plays a key role in immune defense and healing beyond just storing energy.
25 citations,
July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” Imiquimod cream activates hair follicle stem cells and causes early hair growth by changing immune cells and certain protein expressions.
23 citations,
August 2018 in “Biochimica and biophysica acta. Molecular and cell biology of lipids” Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.
32 citations,
March 2019 in “Climacteric” Premature ovarian insufficiency (POI) can harm women's sexual health, and they may benefit from hormone therapy and counseling.
January 2019 in “ARC journal of pharmaceutical sciences” Acne can be managed with various treatments and requires psychological support due to its emotional impact.
21 citations,
November 2018 in “Journal of Psychosomatic Obstetrics & Gynecology” Women with PCOS have more emotional and body image issues than healthy women.
88 citations,
July 2019 in “International Journal of Molecular Sciences” Using human fat tissue derived stem cells in micrografts can safely and effectively increase hair density in people with hair loss.
December 2022 in “International Journal of Molecular Sciences” Afatinib, neratinib, and zanubrutinib could be effective against KRASG12C-mutant tumors.
January 2022 in “International journal of zoology and animal biology” Dogs with dermatomyositis, especially Collies and Shetland Sheepdogs, need better treatments for their skin and muscle inflammation.
January 2023 in “Journal of Clinical and Diagnostic Research” Microneedling with PRP is as effective and safe as minoxidil+finasteride for treating hair loss.
2 citations,
January 2018 in “Recent clinical techniques, results, and research in wounds” Low-Level Laser Therapy helps heal wounds and regenerate tissue when used correctly.
1 citations,
August 2022 in “Frontiers in Physiology” Finasteride may help treat kidney disease caused by a high-fat diet by reducing harmful toxins and improving gut bacteria.
63 citations,
February 2017 in “ACS biomaterials science & engineering” Polydopamine is a safe, effective, and permanent hair dye that turns gray hair black in one hour.
4 citations,
July 2022 in “Frontiers in Cell and Developmental Biology” The document concludes that understanding adult stem cells and their environments can help improve skin regeneration in the future.